Transcription Factor
| Accessions: | UP00007A (UniPROBE 20160601) |
| Names: | A530045N19Rik, early growth response 1, Early growth response protein 1, Egr-1, Egr1, ETR103, Krox-1, Krox-24, Krox-24 protein, Krox24, Nerve growth factor-induced protein A, NGF1-A, NGFI-A, NGFIA, TIS8, Transcription factor Zif268, Zenk, Zfp-6 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P08046 |
| Description: | early growth response 1 |
| Length: | 111 |
| Pfam Domains: | 16-40 C2H2-type zinc finger 16-40 Zinc finger, C2H2 type 33-56 Zinc-finger double domain 46-68 C2H2-type zinc finger 46-68 Zinc finger, C2H2 type 60-84 Zinc-finger double domain 74-92 C2H2-type zinc finger 74-96 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 KYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDH 60 61 LTTHIRTHTGEKPFACDICGRKFARSDDRKRHTKIHLRQKDKKADKSVVAS |
| Interface Residues: | 5, 28, 29, 30, 31, 32, 34, 35, 54, 56, 57, 58, 59, 60, 62, 63, 64, 84, 85, 86, 87, 88, 89, 90, 91, 92 |
| 3D-footprint Homologues: | 5ei9_F, 7n5w_A, 1tf3_A, 6jnm_A, 5k5l_F, 8ssu_A, 1tf6_A, 6ml4_A, 4x9j_A, 2i13_A, 6blw_A, 5kkq_D, 2wbs_A, 1ubd_C, 6u9q_A, 2jpa_A, 1mey_C, 5kl3_A, 7ysf_A, 1f2i_J, 6wmi_A, 2kmk_A, 8ssq_A, 7w1m_H, 5und_A, 2gli_A, 1g2f_F, 5v3j_F, 8h9h_G, 7eyi_G, 2lt7_A, 6e94_A, 6a57_A, 2drp_D, 7y3l_A, 3uk3_C, 8cuc_F, 1llm_D, 5yel_A, 7txc_E, 5k5i_A, 4m9v_C, 7y3m_I, 8gn3_A, 5yj3_D |
| Binding Motifs: | UP00007A_1 yCCGCCCMCgCayt UP00007A_2 kkybGaGkGGGAywrk |
| Binding Sites: | CCGCCCCC ACGCCCCC AGGGGGCG CCACCCCC CCCACGCA CCCACTCA CCCCCCCA CCCCCGCA CCCCCGCG CCCCCTCA CCGCCCAC CGCCCACG CGCCCCCG GAGGGGGC GCCCACGC GCCCCCCC GCCCCCGC GCGGGGGA CCCCCTCG GGGGGCGA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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