Transcription Factor
| Accessions: | P50539 (JASPAR 2024) |
| Names: | bHLHc11, Class C basic helix-loop-helix protein 11, Max interactor 1, Max-interacting protein 1, MXI1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P50539 |
| Length: | 228 |
| Pfam Domains: | 69-120 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSG 60 61 SSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE 120 121 EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD 180 181 VESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS |
| Interface Residues: | 71, 72, 73, 75, 76, 79, 80, 103 |
| 3D-footprint Homologues: | 1an4_A, 6g1l_A, 7d8t_A, 5eyo_A, 7f2f_B, 5i50_B, 7rcu_E |
| Binding Motifs: | MA1108.1 ssrCCACGTGsss MA1108.2 rvCACATGkc MA1108.3 CACATG |
| Binding Sites: | MA1108.3.10 / MA1108.3.11 / MA1108.3.12 / MA1108.3.13 / MA1108.3.14 / MA1108.3.15 / MA1108.3.17 / MA1108.3.18 / MA1108.3.19 / MA1108.3.3 / MA1108.3.4 / MA1108.3.5 / MA1108.3.6 / MA1108.3.7 / MA1108.3.8 / MA1108.3.9 MA1108.3.1 / MA1108.3.2 MA1108.2.10 MA1108.1.1 MA1108.1.10 MA1108.1.11 MA1108.1.12 MA1108.1.13 MA1108.1.14 MA1108.1.15 MA1108.1.16 MA1108.1.17 MA1108.1.18 MA1108.1.19 MA1108.1.2 MA1108.1.20 MA1108.1.3 MA1108.1.4 MA1108.1.5 MA1108.1.6 MA1108.1.7 MA1108.1.8 MA1108.1.9 MA1108.2.1 MA1108.2.11 MA1108.2.12 MA1108.2.13 / MA1108.2.6 MA1108.2.14 / MA1108.2.7 MA1108.2.15 MA1108.2.16 MA1108.2.17 MA1108.2.18 MA1108.2.19 / MA1108.2.8 MA1108.2.2 MA1108.2.20 / MA1108.2.9 MA1108.2.3 MA1108.2.4 MA1108.2.1 / MA1108.2.5 MA1108.2.2 / MA1108.2.6 MA1108.2.3 / MA1108.2.7 MA1108.2.4 / MA1108.2.8 MA1108.2.5 / MA1108.2.9 MA1108.2.10 / MA1108.2.12 MA1108.2.11 MA1108.2.13 MA1108.2.14 MA1108.2.15 MA1108.2.16 MA1108.2.17 MA1108.2.18 MA1108.2.19 MA1108.2.20 MA1108.3.16 MA1108.3.20 |
| Publications: | Zervos A. S., Gyuris J., Brent R. Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72:223-232 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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