Transcription Factor

Accessions: 4xrs_I (3D-footprint 20231221)
Names: DLX3_HUMAN, Homeobox protein DLX-3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O60479
Length: 56
Pfam Domains: 1-56 Homeobox domain
Sequence:
(in bold interface residues)
1 KPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK
Interface Residues: 1, 2, 3, 41, 42, 44, 45, 48, 49, 52, 53, 56
3D-footprint Homologues: 2lkx_A, 6m3d_C, 1nk2_P, 1zq3_P, 6es3_K, 2ld5_A, 7q3o_C, 3a01_E, 2h1k_B, 1b72_A, 5flv_I, 3lnq_A, 1puf_A, 1ig7_A, 5zjt_E, 3cmy_A, 2hdd_A, 5hod_A, 3rkq_B, 2r5y_A, 1jgg_B, 6a8r_A, 3d1n_M, 2hos_A, 7psx_B, 5jlw_D, 4cyc_A, 1au7_A, 4xrs_G, 1fjl_B, 5zfz_A, 4j19_B, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 6fqq_E, 4qtr_D, 1mnm_C, 1du0_A, 1puf_B, 8g87_X, 4xrm_B, 1k61_B, 3l1p_A, 1o4x_A
Binding Motifs: 4xrs_BI ganmngatA
Binding Sites: 4xrs_D
4xrs_E
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Related annotations: PaperBLAST

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