Transcription Factor

Accessions: Q9VEI9 (JASPAR 2024)
Names: DHmx, HMX_DROME, Homeobox protein Hmx
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 592
Pfam Domains: 469-525 Homeobox domain
Sequence:
(in bold interface residues)
1 MSSSEAEVDISVVSSPEPSPLGAAARDSPLLARSPARSADGSSPPATPTHRSNTPNTAAG 60
61 TPTTSASGGNHFHHSPSGGAVPPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGA 120
121 THPALLQHALTPTGQQQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNS 180
181 KALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSIL 240
241 SRSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWP 300
301 WAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPL 360
361 YHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHL 420
421 TGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQV 480
481 FQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMA 540
541 HAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAAARNTSPPRPPLSSLV
Interface Residues: 468, 469, 470, 471, 472, 510, 511, 513, 514, 517, 518, 521, 522, 525
3D-footprint Homologues: 4j19_B, 1fjl_B, 2h1k_B, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 3d1n_M, 5zfz_A, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 5zjt_E, 3a01_E, 7psx_B, 1b72_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 4cyc_A, 1au7_A, 5flv_I, 3l1p_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1o4x_A, 8g87_X, 5hod_A, 4qtr_D, 1mnm_C, 1du0_A, 1puf_B, 1k61_B
Binding Motifs: MA0192.1 TTAATTG
Binding Sites: MA0192.1.17
MA0192.1.18
MA0192.1.7
MA0192.1.1
MA0192.1.10
MA0192.1.11
MA0192.1.12
MA0192.1.13
MA0192.1.14
MA0192.1.15
MA0192.1.16
MA0192.1.19
MA0192.1.2
MA0192.1.20
MA0192.1.3
MA0192.1.4
MA0192.1.5
MA0192.1.6
MA0192.1.8
MA0192.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.