Transcription Factor
| Accessions: | ovo (DrosophilaTF 1.1), P51521 (JASPAR 2024) |
| Names: | OVO_DROME, Protein ovo, Protein shaven baby, Transcriptional activator svb, Transcriptional regulator ovo, Transcriptional repressor shavenbaby, Transcriptional repressor svb |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P51521 |
| Length: | 1352 |
| Pfam Domains: | 1212-1235 Zinc-finger double domain 1225-1247 Zinc finger, C2H2 type 1239-1264 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MPKIFLIKNRLHQQQQRLLESQNLLQHKNQDDERLVPPLSPSGSGSGPSPTPTSQPPPEP 60 61 QGQGQQVLGQVPDSDQQPLSLTRKRFHHRRHYFGQSRHSLDHLNQNQSPNPNANANPNQI 120 121 QNPAELEVECATGQVQNENFAAELLQRLTPNTATTAQNNIVNNLVNNSRAATSVLATKDC 180 181 TIENSPISIPKNQRAEDEEEQEDQEKEKPAEREREKSDERTEQVEKEERVEREEEEDDEV 240 241 DVGVEAPRPRFYNTGVVLTQAQRKEYPQEPKDLSLTIAKSSPASPHIHSDSESDSDSDGG 300 301 CKLIVDEKPPLPVIKPLSLRLRSTPPPADQRPSPPPPRDPAPAVRCSVIQRAPQSQLPTS 360 361 RAGFLLPPLDQLGPEQQEPIDYHVPKRRSPSYDSDEELNARRLERARQVREARRRSTILA 420 421 ARVLLAQSQRLNPRLVRSLPGILAAAAGHGRNSSSSSGAAGQGFQSSGFGSQNSGSGSSS 480 481 GNQNAGSGAGSPGSGAGGGGGMGGGRDGRGNYGPNSPPTGALPPFYESLKSGQQSTASNN 540 541 TGQSPGANHSHFNANPANFLQNAAAAAYIMSAGSGGGGCTGNGGGGASGPGGGPSANSGG 600 601 GGGGGGGNGYINCGGVGGPNNSLDGNNLLNFASVSNYNESNSKFHNHHHHHQHNNNNNNN 660 661 GGQTSMMGHPFYGGNPSAYGIILKDEPDIEYDEAKIDIGTFAQNIIQATMGSSGQFNASA 720 721 YEDAIMSDLASSGQCPNGAVDPLQFTATLMLSSQTDHLLEQLSDAVDLSSFLQRSCVDDE 780 781 ESTSPRQDFELVSTPSLTPDSVTPVEQHNTNTTQLDVLHENLLTQLTHNIVRGGSNQQQQ 840 841 HHQQHGVQQQQQQQHSVQQQQQHNVQQQHGVQQQHVQQQPPPSYQHATRGLMMQQQPQHG 900 901 GYQQQAAIMSQQQQQLLSQQQQQSHHQQQQQQQHAAAYQQHNIYAQQQQQQQQQHHQQQQ 960 961 QQQHHHFHHQQQQQPQPQSHHSHHHGHGHDNSNMSLPSPTAAAAAAAAAAAAAAAA AAH 1020 1021 LQRPMSSSSSSGGTNSSNSSGGSSNSPLLDANAAAAAAAALLDTKPLIQSLGLPPDLQLE 1080 1081 FVNGGHGIKNPLAVENAHGGHHRIRNIDCIDDLSKHGHHSQHQQQQGSPQQQNMQQSVQQ 1140 1141 QSVQQQQSLQQQQQQQHHQHHSNSSASSNASSHGSAEALCMGSSGGANEDSSSGNNKFVC 1200 1201 RVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCE 1260 1261 KSFTQRCSLESHCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSP 1320 1321 ALLKFYDKRHFKFTNSQFANNLLGQLPMPVHN |
| Interface Residues: | 1197, 1207, 1208, 1209, 1210, 1211, 1213, 1214, 1235, 1236, 1237, 1238, 1239, 1241, 1242, 1243, 1263, 1264, 1265, 1266, 1267, 1268, 1269, 1270, 1271, 1274, 1284, 1287, 1290, 1300, 1302, 1303, 1305, 1306, 1309, 1330, 1331 |
| 3D-footprint Homologues: | 2kmk_A, 1tf3_A, 1g2f_F, 7n5w_A, 6jnm_A, 8ssu_A, 5v3j_F, 2gli_A, 8gn3_A, 6blw_A, 5kkq_D, 1tf6_A, 4x9j_A, 1llm_D, 5kl3_A, 1ubd_C, 6wmi_A, 5ei9_F, 2jpa_A, 8ssq_A, 1mey_C, 7w1m_H, 5und_A, 7eyi_G, 8h9h_G, 2lt7_A, 2i13_A, 6e94_A, 7ysf_A, 6a57_A, 7y3l_A, 3uk3_C, 8cuc_F, 5k5i_A, 6ml4_A, 6u9q_A, 5yel_A, 7txc_E, 2wbs_A, 2drp_D, 1f2i_J, 4m9v_C, 7y3m_I, 5yj3_D |
| Binding Motifs: | MA0126.1 wgtAACwGt ovo wgtAACaGw MA0126.2 wgtAACwG |
| Binding Sites: | MA0126.2.3 ovo_100 ovo_102 ovo_106 ovo_129 ovo_130 ovo_15rc ovo_180 ovo_19rc ovo_20 ovo_208 ovo_216 ovo_25 ovo_26 ovo_37 ovo_4 ovo_60 ovo_69 ovo_74rc ovo_83 ovo_90 ovo_99 MA0126.2.2 MA0126.1.1 MA0126.1.10 MA0126.1.11 MA0126.1.12 MA0126.1.13 MA0126.1.14 MA0126.1.15 MA0126.1.16 MA0126.1.17 MA0126.1.18 MA0126.1.19 MA0126.1.2 MA0126.1.20 MA0126.1.3 MA0126.1.4 MA0126.1.5 MA0126.1.6 MA0126.1.7 MA0126.1.8 MA0126.1.9 MA0126.2.1 MA0126.2.10 MA0126.2.11 MA0126.2.12 MA0126.2.13 MA0126.2.14 MA0126.2.15 MA0126.2.16 MA0126.2.17 MA0126.2.18 MA0126.2.19 MA0126.2.20 MA0126.2.4 MA0126.2.5 MA0126.2.6 MA0126.2.7 MA0126.2.8 MA0126.2.9 |
| Publications: | Lee S., Garfinkel M. D. Characterization of Drosophila OVO protein DNA binding specificity using random DNA oligomer selection suggests zinc finger degeneration.. Nucleic Acids Res. 28:826-834 (2000). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.