Transcription Factor
| Accessions: | Q0WV12 (JASPAR 2024), T18833 (AthalianaCistrome v4_May2016) |
| Names: | ANL2_ARATH, HD-ZIP protein ANL2, Homeobox-leucine zipper protein ANTHOCYANINLESS 2, Homeodomain protein AHDP, Homeodomain transcription factor ANL2, ANL2, AT4G00730, T18833; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:HB |
| Length: | 802 |
| Pfam Domains: | 135-190 Homeobox domain 324-543 START domain |
| Sequence: (in bold interface residues) | 1 MNFGSLFDNTPGGGSTGARLLSGLSYGNHTAATNVLPGGAMAQAAAAASLFSPPLTKSVY 60 61 ASSGLSLALEQPERGTNRGEASMRNNNNVGGGGDTFDGSVNRRSREEEHESRSGSDNVEG 120 121 ISGEDQDAADKPPRKKRYHRHTPQQIQELESMFKECPHPDEKQRLELSKRLCLETRQVKF 180 181 WFQNRRTQMKTQLERHENALLRQENDKLRAENMSIREAMRNPICTNCGGPAMLGDVSLEE 240 241 HHLRIENARLKDELDRVCNLTGKFLGHHHNHHYNSSLELAVGTNNNGGHFAFPPDFGGGG 300 301 GCLPPQQQQSTVINGIDQKSVLLELALTAMDELVKLAQSEEPLWVKSLDGERDELNQDEY 360 361 MRTFSSTKPTGLATEASRTSGMVIINSLALVETLMDSNRWTEMFPCNVARATTTDVISGG 420 421 MAGTINGALQLMNAELQVLSPLVPVRNVNFLRFCKQHAEGVWAVVDVSIDPVRENSGGAP 480 481 VIRRLPSGCVVQDVSNGYSKVTWVEHAEYDENQIHQLYRPLLRSGLGFGSQRWLATLQRQ 540 541 CECLAILISSSVTSHDNTSITPGGRKSMLKLAQRMTFNFCSGISAPSVHNWSKLTVGNVD 600 601 PDVRVMTRKSVDDPGEPPGIVLSAATSVWLPAAPQRLYDFLRNERMRCEWDILSNGGPMQ 660 661 EMAHITKGQDQGVSLLRSNAMNANQSSMLILQETCIDASGALVVYAPVDIPAMHVVMNGG 720 721 DSSYVALLPSGFAVLPDGGIDGGGSGDGDQRPVGGGSLLTVAFQILVNNLPTAKLTVESV 780 781 ETVNNLISCTVQKIRAALQCES |
| Interface Residues: | 134, 135, 136, 137, 138, 139, 140, 176, 177, 179, 180, 183, 184, 187, 188, 190, 191 |
| 3D-footprint Homologues: | 1puf_A, 3a01_E, 6a8r_A, 2h1k_B, 2lkx_A, 1zq3_P, 2ld5_A, 1puf_B, 1mnm_C, 7psx_B, 3d1n_M, 5zjt_E, 1nk2_P, 3rkq_B, 7q3o_C, 1k61_B, 6es3_K, 3l1p_A, 2r5y_A, 5jlw_D, 1ig7_A, 4j19_B, 1e3o_C, 1au7_A, 2xsd_C, 7xrc_C, 1le8_A, 6wig_A, 5zfz_A, 8g87_X, 6fqp_B, 1du0_A, 5flv_I, 3lnq_A, 1jgg_B, 4qtr_D, 3cmy_A, 2hdd_A, 6fqq_E, 5hod_A, 4xrm_B, 1o4x_A, 1fjl_B, 4cyc_A, 2d5v_B, 1b72_A, 4xrs_G, 2hos_A, 6m3d_C |
| Binding Motifs: | M0417 / MA1375.1 gCATTAAwTry M0421 gCATTAAwTry MA1375.2 gCATTAAwTr |
| Binding Sites: | MA1375.1.5 MA1375.1.14 MA1375.1.19 MA1375.1.8 MA1375.1.17 MA1375.1.20 MA1375.1.1 MA1375.1.10 MA1375.1.11 MA1375.1.12 MA1375.1.13 MA1375.1.15 MA1375.1.16 MA1375.1.18 MA1375.1.2 MA1375.1.3 MA1375.1.4 MA1375.1.6 MA1375.1.7 MA1375.1.9 MA1375.2.1 MA1375.2.10 MA1375.2.11 MA1375.2.12 MA1375.2.13 MA1375.2.14 MA1375.2.15 MA1375.2.16 MA1375.2.17 MA1375.2.18 MA1375.2.19 MA1375.2.2 MA1375.2.20 MA1375.2.3 MA1375.2.4 MA1375.2.5 MA1375.2.6 MA1375.2.7 MA1375.2.8 MA1375.2.9 |
| Publications: | Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Related annotations: | PaperBLAST |
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