Transcription Factor

Accessions: 4atk_A (3D-footprint 20231221)
Names: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR, MITF_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q08874
Length: 60
Pfam Domains: 2-50 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 DNHNLIERRRRFNINDRIKELGTLIPKDPDMRWNKGTILKASVDYIRKLQREQQRAKDLE 60
Interface Residues: 3, 4, 6, 7, 10, 11, 33, 35
3D-footprint Homologues: 7d8t_A, 5gnj_I, 1am9_A, 7xi3_A, 5v0l_A, 7f2f_B, 5i50_B, 4zpk_A, 7rcu_E, 6g1l_A, 5eyo_A, 1a0a_B, 7ssa_L, 5nj8_D, 4h10_A, 8osl_P, 4h10_B, 1an4_A, 8osl_O, 7z5k_B, 5nj8_C, 2ypa_A, 5v0l_B
Binding Motifs: 4atk_AB AGCACGTGC
Publications: Pogenberg V, Ogmundsdóttir M.H, Bergsteinsdóttir K, Schepsky A, Phung B, Deineko V, Milewski M, Steingrímsson E, Wilmanns M. Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF. Genes & development 26:2647-58 (2012). [Pubmed]
Related annotations: PaperBLAST

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