Transcription Factor

Accessions: 6a57_A (3D-footprint 20231221)
Names: EC 1.14.11.-, Jumonji domain-containing protein 12, Lysine-specific demethylase REF6, Lysine-specific histone demethylase REF6, Protein RELATIVE OF EARLY FLOWERING 6, REF6_ARATH
Organisms: Arabidopsis thaliana
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9STM3
Length: 131
Pfam Domains: 19-42 C2H2-type zinc finger
19-44 Zinc finger, C2H2 type
43-66 C2H2-type zinc finger
44-66 Zinc finger, C2H2 type
59-84 Zinc-finger double domain
73-96 C2H2-type zinc finger
90-113 Zinc-finger double domain
102-128 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 EKEEEEEEEENEEEECAAYQCNMEGCTMSFSSEKQLMLHKRNICPIKGCGKNFFSHKYLV 60
61 QHQRVHSDDRPLKCPWKGCKMTFKWAWSRTEHIRVHTGARPYVCAEPDCGQTFRFVSDFS 120
121 RHKRKTGHSVK
Interface Residues: 32, 34, 35, 37, 38, 40, 41, 42, 54, 55, 56, 57, 58, 60, 61, 65, 84, 85, 86, 87, 88, 89, 90, 91, 92, 95, 114, 115, 116, 117, 118, 119, 120, 121, 122
3D-footprint Homologues: 1tf6_A, 6wmi_A, 5ei9_F, 5v3j_F, 2i13_A, 1ubd_C, 2jpa_A, 6jnm_A, 3uk3_C, 8cuc_F, 7y3l_A, 6ml4_A, 7n5w_A, 1tf3_A, 5kl3_A, 7ysf_A, 7eyi_G, 2kmk_A, 1mey_C, 1f2i_J, 6blw_A, 5kkq_D, 6u9q_A, 4x9j_A, 1g2f_F, 7txc_E, 2gli_A, 8h9h_G, 2lt7_A, 6e94_A, 6a57_A, 7w1m_H, 5und_A, 2wbs_A, 8ssq_A, 1llm_D, 5k5i_A, 8gn3_A, 5yel_A, 4m9v_C, 7y3m_I, 5yj3_D
Binding Motifs: 6a57_A ACAGAG
Binding Sites: 6a57_B
6a57_C
Publications: Tian Z, Li X, Li M, Wu W, Zhang M, Tang C, Li Z, Liu Y, Chen Z, Yang M, Ma L, Caba C, Tong Y, Lam HM, Dai S, Chen Z. Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms. Cell Discov : (2020). [Pubmed]
Related annotations: PaperBLAST

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