Transcription Factor
| Accessions: | Q5FWF6 (JASPAR 2024) |
| Names: | ZN789_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q5FWF6 |
| Length: | 425 |
| Pfam Domains: | 12-51 KRAB box 201-223 Zinc finger, C2H2 type 201-209 C2H2-type zinc finger 201-223 C2H2-type zinc finger 217-239 Zinc-finger double domain 228-253 C2H2-type zinc finger 229-249 C2H2-type zinc finger 229-248 Zinc finger, C2H2 type 257-279 Zinc finger, C2H2 type 257-277 C2H2-type zinc finger 272-295 Zinc-finger double domain 284-303 C2H2-type zinc finger 285-305 C2H2-type zinc finger 285-307 Zinc finger, C2H2 type 300-323 Zinc-finger double domain 313-333 C2H2-type zinc finger 313-335 Zinc finger, C2H2 type 328-351 Zinc-finger double domain 340-361 C2H2-type zinc finger 341-363 C2H2-type zinc finger 341-363 Zinc finger, C2H2 type 356-379 Zinc-finger double domain 369-389 C2H2-type zinc finger 369-387 C2H2-type zinc finger 369-391 Zinc finger, C2H2 type 383-407 Zinc-finger double domain 397-419 C2H2-type zinc finger 397-416 C2H2-type zinc finger 397-419 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MFPPARGKELLSFEDVAMYFTREEWGHLNWGQKDLYRDVMLENYRNMVLLGFQFPKPEMI 60 61 CQLENWDEQWILDLPRTGNRKASGSACPGSEARHKMKKLTPKQKFSEDLESYKISVVMQE 120 121 SAEKLSEKLHKCKEFVDSCRLTFPTSGDEYSRGFLQNLNLIQDQNAQTRWKQGRYDEDGK 180 181 PFNQRSLLLGHERILTRAKSYECSECGKVIRRKAWFDQHQRIHFLENPFECKVCGQAFRQ 240 241 RSALTVHKQCHLQNKPYRCHDCGKCFRQLAYLVEHKRIHTKEKPYKCSKCEKTFSQNSTL 300 301 IRHQVIHSGEKRHKCLECGKAFGRHSTLLCHQQIHSKPNTHKCSECGQSFGRNVDLIQHQ 360 361 RIHTKEEFFQCGECGKTFSFKRNLFRHQVIHTGSQPYQCVICGKSFKWHTSFIKHQGTHK 420 421 GQIST |
| Interface Residues: | 183, 187, 211, 212, 213, 214, 215, 218, 222, 229, 240, 241, 242, 243, 246, 267, 268, 270, 271, 273, 274, 276, 277, 280, 295, 296, 297, 298, 299, 301, 302, 320, 324, 325, 326, 327, 330, 352, 353, 354, 355, 358, 364, 378, 380, 382, 383, 386, 390, 407, 408, 410, 411, 414 |
| 3D-footprint Homologues: | 7w1m_H, 7y3l_A, 7n5w_A, 8cuc_F, 8ssu_A, 5v3j_F, 8ssq_A, 7ysf_A, 2kmk_A, 2gli_A, 7txc_E, 6e94_A, 1tf3_A, 1tf6_A, 6u9q_A, 2lt7_A, 2jpa_A, 2drp_D, 8h9h_G, 1ubd_C, 7y3m_I, 8gn3_A |
| Binding Motifs: | UN0660.1 dkcTCCCACTyCTGaCACCaam UN0660.2 cTCCCACTyCTGaCACCa |
| Binding Sites: | UN0660.1.1 UN0660.1.10 / UN0660.1.11 UN0660.1.11 / UN0660.1.12 UN0660.1.12 / UN0660.1.13 UN0660.1.13 / UN0660.1.15 UN0660.1.14 / UN0660.1.16 UN0660.1.15 / UN0660.1.17 UN0660.1.16 / UN0660.1.19 UN0660.1.17 / UN0660.1.20 UN0660.1.18 UN0660.1.19 UN0660.1.2 UN0660.1.20 UN0660.1.3 UN0660.1.4 UN0660.1.5 UN0660.1.6 UN0660.1.7 UN0660.1.8 UN0660.1.10 / UN0660.1.9 UN0660.1.14 UN0660.1.18 UN0660.1.9 UN0660.2.1 UN0660.2.10 UN0660.2.11 UN0660.2.12 UN0660.2.13 UN0660.2.14 UN0660.2.15 UN0660.2.16 UN0660.2.17 UN0660.2.18 UN0660.2.19 UN0660.2.2 UN0660.2.20 UN0660.2.3 UN0660.2.4 UN0660.2.5 UN0660.2.6 UN0660.2.7 UN0660.2.8 UN0660.2.9 |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.