Transcription Factor
| Accessions: | P16220 (JASPAR 2024) |
| Names: | cAMP-responsive element-binding protein 1, CREB-1, CREB1_HUMAN, Cyclic AMP-responsive element-binding protein 1 |
| Organisms: | Homo sapiens, Rattus norvegicus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 327 |
| Pfam Domains: | 99-139 pKID domain 267-324 bZIP transcription factor 272-319 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPN 60 61 GQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSY 120 121 RKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLA 180 181 NNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQI 240 241 RTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENR 300 301 VAVLENQNKTLIEELKALKDLYCHKSD |
| Interface Residues: | 275, 279, 280, 282, 283, 286, 287 |
| 3D-footprint Homologues: | 7x5e_F, 4eot_A, 5t01_B, 5vpe_D, 1dh3_C |
| Binding Motifs: | MA0018.2 TGACGYcA MA0018.1 bbkGrTGACGym MA0018.3 grTGACGTCAyc MA0018.4 wdrTGATGTCAyh MA0018.5 TGATGTCA |
| Binding Sites: | MA0018.5.1 / MA0018.5.10 / MA0018.5.11 / MA0018.5.12 / MA0018.5.13 / MA0018.5.14 / MA0018.5.2 / MA0018.5.3 / MA0018.5.4 / MA0018.5.6 / MA0018.5.7 / MA0018.5.9 MA0018.2.7 MA0018.5.18 MA0018.1.1 MA0018.1.10 MA0018.1.11 MA0018.1.12 MA0018.1.13 MA0018.1.14 MA0018.1.15 MA0018.1.16 MA0018.1.2 MA0018.1.3 MA0018.1.4 MA0018.1.5 MA0018.1.6 MA0018.1.7 MA0018.1.8 MA0018.1.9 MA0018.2.1 MA0018.2.10 MA0018.2.11 MA0018.2.2 MA0018.2.3 MA0018.2.4 MA0018.2.5 MA0018.2.6 MA0018.2.8 MA0018.2.9 MA0018.3.1 MA0018.3.10 MA0018.3.11 / MA0018.3.12 MA0018.3.13 MA0018.3.14 MA0018.3.15 MA0018.3.16 MA0018.3.17 MA0018.3.18 MA0018.3.19 MA0018.3.2 MA0018.3.20 MA0018.3.3 MA0018.3.4 MA0018.3.5 MA0018.3.6 MA0018.3.7 MA0018.3.8 MA0018.3.9 MA0018.5.20 MA0018.4.1 MA0018.4.10 MA0018.4.11 MA0018.4.12 MA0018.4.13 MA0018.4.14 MA0018.4.15 MA0018.4.16 / MA0018.4.6 MA0018.4.17 / MA0018.4.7 MA0018.4.18 MA0018.4.19 / MA0018.4.8 MA0018.4.2 MA0018.4.10 / MA0018.4.20 / MA0018.4.9 MA0018.4.3 MA0018.4.4 MA0018.4.5 MA0018.4.6 MA0018.4.7 MA0018.4.8 MA0018.4.5 / MA0018.4.9 MA0018.4.20 MA0018.4.11 MA0018.4.12 MA0018.4.13 MA0018.4.14 MA0018.4.15 MA0018.4.16 MA0018.4.17 MA0018.4.18 MA0018.4.19 MA0018.5.15 MA0018.5.16 / MA0018.5.17 MA0018.5.19 MA0018.5.5 MA0018.5.8 |
| Publications: | Paca-Uccaralertkun S., Zhao L.-J., Adya N., Cross J. V., Cullen B. R., Boros I. M., Giam C.-Z. In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax. Mol. Cell. Biol. 14:456-462 (1994). [Pubmed] Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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