Transcription Factor

Accessions: T134195_1.02 (CISBP 1.02)
Names: nhr-7, T134195_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 536
Pfam Domains: 8-76 Zinc finger, C4 type (two domains)
296-499 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MQSYTNRICAVCGDTPAKIHYGVLACFGCKGFFRRAVKDGRNKYVCRFEKNCEVTKFERN 60
61 ACRYCRFRKCLLVGMNPDYVRPDREKSKKGKTVLSKKKSVSRSLSYRLADPSDWTSFLSP 120
121 SSRKQLSEIGKLAETCSTSTNFDGIGNFSLKSLIADRSLARKTGDSEAMDCSNSPRQLNE 180
181 QFLGIERIVQCVDYIDRFLVMLEEEHCRKFSVEDKSALISDTMIHLLLFESTSRFVAKGA 240
241 PGLEDLKLSLAQLPICTTHLTQKIADVFETYLRKPPSIIEYSVLKAYIVLSAESTVLSNS 300
301 LNESLSLARENLSELLFKVIKHSRNKTSISAANSLSTILHFVYESRNLASRIRQSQQPFF 360
361 VRDSDPKIPFHKILTDIINPEVSDLLLTTANCRKLSTQMGSSLSSVPPVPPPSDTVPLFH 420
421 FSPPSLSPCQISAPPPPQQQYTDYSQMPSTSSYPANSSPFQSPYRPNSLSSFPKIPLEMT 480
481 KSIEEFLRPNGMTTDEMNKPLEKNWADGFRLTPVFNKDIVSQFFPELSNINQHHPF
Interface Residues: 17, 18, 20, 21, 27, 28, 30, 31, 34, 35, 60, 82, 84, 86, 89, 91
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B
Binding Motifs: M1467_1.02 kTGrTCTTt
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.