Transcription Factor
| Accessions: | UP00086A (UniPROBE 20160601) |
| Names: | C920001K05Rik, interferon regulatory factor 3, IRF-3, Irf3, MGC91046 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P70671 |
| Description: | interferon regulatory factor 3 |
| Length: | 127 |
| Pfam Domains: | 7-110 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 METPKPRILPWLVSQLDLGQLEGVAWLDESRTRFRIPWKHGLRQDAQMADFGIFQAWAEA 60 61 SGAYTPGKDKPDVSTWKRNFRSALNRKEVLRLAADNSKDPYDPHKVYEFVTPGARDFVHL 120 121 GASPDTN |
| Interface Residues: | 40, 42, 74, 78, 79, 81, 82, 85, 86 |
| 3D-footprint Homologues: | 1if1_B, 2o61_A, 2pi0_B, 2irf_L, 7oot_B |
| Binding Motifs: | UP00086A_1 garAAhsGAAACyr UP00086A_2 ggagAAwGGwscra |
| Binding Sites: | AAAGGAAA AAGGAAAC ACCGAAAC AGAAAGGA AGGAAACT AGTTTCCA AGTTTCGA ATCGAAAC ATGGAAAC CAGTTTCC CGAAACCG CGGTTTCC GAAACCAA GGAAACTA GGTTTCCA GTTTCCAA GTTTCGAA GTTTCGGA TTTCCAAA TTTCGAAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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