Transcription Factor

						

			
Accessions: 5ipl_F (3D-footprint 20231221), 5ipm_F (3D-footprint 20231221), 5ipn_F (3D-footprint 20231221)

			
Names: RNA polymerase sigma factor RpoS, RPOS_ECOLI, Sigma S, Sigma-38
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P13445
Length: 277
Pfam Domains:      4-37 Sigma-70 factor, region 1.2
   42-112 Sigma-70 region 2 
  122-197 Sigma-70 region 3
  210-263 Sigma-70, region 4
Sequence: 
(in bold interface residues)		   1 RVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNR   60
  61 GLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHIV  120
 121 KELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGDSEK  180
 181 ALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVG  240
 241 REIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFL
Interface Residues: 236, 237, 246, 247, 248, 249, 251, 252
3D-footprint Homologues: 3n97_A, 6ido_B, 8cyf_B, 6wpa_A
Binding Motifs: 5ipl_F TATGCTATAATGTGTG
5ipm_F TATGCTATAATGTgtg
5ipn_F TATGCTATAATGTnTG
Binding Sites: 5ipl_1 / 5ipm_1 / 5ipn_1
5ipl_2 / 5ipm_2 / 5ipn_2
			
Publications: Liu B, Zuo Y, Steitz TA. Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism : (Proc). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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