Transcription Factor

Accessions: UP00318A (UniPROBE 20160601)
Names: Gln3, Nitrogen regulatory protein GLN3, YER040W
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P18494
Description: Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source
Length: 135
Pfam Domains: 51-85 GATA zinc finger
Sequence:
(in bold interface residues)
1 SSNTTNSVRKNSLIKPMSSTSLANFKRAASVSSSISNMEPSGQNKKPLIQCFNCKTFKTP 60
61 LWRRSPEGNTLCNACGLFQKLHGTMRPLSLKSDVIKKRISKKRAKQTDPNIAQNTPSAPA 120
121 TASTSVTTTNAKPIR
Interface Residues: 60, 61, 63, 73, 77, 78, 81, 98
3D-footprint Homologues: 1gat_A, 3dfx_B, 3vd6_C, 4gat_A
Binding Motifs: UP00318A_1 rkwwhGsCcTTATCarsmmwa
Binding Sites: AAGATAAG
AGATAAGC
AGCTTATC
ATGATAAG
CCGATAAG
CCTTATCA
CCTTATCG
CGATAAGA
CGCTTATC
CTGATAAC
CTTATCAA
CTTATCGC
GATAAGAA
GCGATAAC
GCTGATTA
GCTTATCA
TTATCAAA
ACTTATCG
CCGATAAC
CTTATCGA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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