Transcription Factor
Accessions: | 4eot_B (3D-footprint 20231221) |
Names: | MAFA_HUMAN, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, Transcription factor MafA, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q8NHW3 |
Length: | 92 |
Pfam Domains: | 1-91 bZIP Maf transcription factor |
Sequence: (in bold interface residues) | 1 FSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEK 60 61 CQLQSQVEQLKLEVGRLAKERDLYKEKYEKLA |
Interface Residues: | 34, 38, 41, 42, 45, 46 |
3D-footprint Homologues: | 7x5e_F, 2wt7_B, 4eot_A, 7x5e_E, 2wt7_A |
Binding Motifs: | 4eot_AB tGCnnACTnnGCa |
Binding Sites: | 4eot_C 4eot_D |
Publications: | Lu X, Guanga G.P, Wan C, Rose R.B. A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities. Biochemistry : (2012). [Pubmed] |
Related annotations: | PaperBLAST |
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