Transcription Factor

Accessions: 4eot_B (3D-footprint 20231221)
Names: MAFA_HUMAN, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, Transcription factor MafA, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8NHW3
Length: 92
Pfam Domains: 1-91 bZIP Maf transcription factor
Sequence:
(in bold interface residues)
1 FSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEK 60
61 CQLQSQVEQLKLEVGRLAKERDLYKEKYEKLA
Interface Residues: 34, 38, 41, 42, 45, 46
3D-footprint Homologues: 7x5e_E, 7x5e_F, 2wt7_B, 4eot_A, 2wt7_A
Binding Motifs: 4eot_AB tGCnnACTnnGCa
Binding Sites: 4eot_C
4eot_D
Publications: Lu X, Guanga G.P, Wan C, Rose R.B. A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities. Biochemistry : (2012). [Pubmed]
Related annotations: PaperBLAST

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