Transcription Factor
| Accessions: | FLI1 (HT-SELEX2 May2017) |
| Names: | ENSG00000151702, FLI1 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: ETS experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 284 |
| Pfam Domains: | 18-101 Sterile alpha motif (SAM)/Pointed domain 184-266 Ets-domain |
| Sequence: (in bold interface residues) | 1 SNPMNYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDT 60 61 SFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSV 120 121 KEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANP 180 181 GSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLS 240 241 RALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYK |
| Interface Residues: | 182, 237, 238, 240, 241, 242, 244, 245, 259 |
| 3D-footprint Homologues: | 3zp5_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A |
| Binding Motifs: | FLI1_3 raCCGGAWrys FLI1_4 raCCGGAwwTCCGGty FLI1_7 rACCGGAAryg FLI1_8 rACCGGATATCCGGTy FLI1_methyl_1 raCmGGAArts FLI1_methyl_2 rACCGGAwwTCCGGTy FLI1_methyl_5 grCMGGAWrTs FLI1_methyl_6 vACCGGAWWTCCGGTb |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.