Transcription Factor

Accessions: T017935_1.02 (CISBP 1.02)
Names: NCU00144, T017935_1.02;
Organisms: Neurospora crassa
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 473
Pfam Domains: 329-417 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MMTEVPSAFSLGSGPKGLGIPEHATYSENQTTSIHTTHQRSGPSLPYPNFASSARQTTLA 60
61 TSPSFPVTTASYHVPTPENPTQPPYYQQGAGWEQQQLPSTSAAALYNREHTAVPAPPALT 120
121 PYEFAPSHDISGSCLGDGSTYGSPPVVQSPIQPGFGFLWANGHPPNSVGSNTPSQRAIAS 180
181 PTARTFESISAPSDTGFSDHSDGVAYANIDERANHQQQQQQQQQSQQHRWVQTTTVSMEG 240
241 CNKSEDGPWNTGEKKAFGQIMTPISCASPFNAAAAVPPAVPGGAAKAAKGTASATAALSK 300
301 NKGKLRSASRAPKNIQPRPEETPEERKSRNSHNLVEKQYRNRLNAQFERLLAVLPDSVRS 360
361 SMTMIGGCGGDPDGVNGNGGGGSVIPGQHPSLDFSIERRLSKAEVLDMSRRYILSLEKER 420
421 DTLEREKEQLMHSIDQLRQGHGHPSHGGHAGAMYLVDRNGIPIGHGHMRGVGG
Interface Residues: 331, 332, 333, 335, 336, 339, 340
3D-footprint Homologues: 1an4_A, 5gnj_I, 7d8t_A, 1am9_A, 5i50_B, 7f2f_B, 5nj8_D, 8hov_A, 4h10_B, 6g1l_A, 8ia3_B
Binding Motifs: M0230_1.02 rtcAygyga
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.