Transcription Factor

Accessions: Q9H4T2 (JASPAR 2024)
Names: Zinc finger and SCAN domain-containing protein 16, Zinc finger protein 392, Zinc finger protein 435, ZSC16_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9H4T2
Length: 348
Pfam Domains: 36-129 SCAN domain
236-258 C2H2-type zinc finger
236-258 Zinc finger, C2H2 type
236-258 C2H2-type zinc finger
250-273 Zinc-finger double domain
263-279 C2H2-type zinc finger
264-286 C2H2-type zinc finger
264-286 Zinc finger, C2H2 type
282-302 Zinc-finger double domain
291-312 C2H2-type zinc finger
292-314 C2H2-type zinc finger
292-314 Zinc finger, C2H2 type
307-329 Zinc-finger double domain
319-340 C2H2-type zinc finger
320-342 C2H2-type zinc finger
320-342 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MTTALEPEDQKGLLIIKAEDHYWGQDSSSQKCSPHRRELYRQHFRKLCYQDAPGPREALT 60
61 QLWELCRQWLRPECHTKEQILDLLVLEQFLSILPKDLQAWVRAHHPETGEEAVTVLEDLE 120
121 RELDEPGKQVPGNSERRDILMDKLAPLGRPYESLTVQLHPKKTQLEQEAGKPQRNGDKTR 180
181 TKNEELFQKEDMPKDKEFLGEINDRLNKDTPQHPKSKDIIENEGRSEWQQRERRRYKCDE 240
241 CGKSFSHSSDLSKHRRTHTGEKPYKCDECGKAFIQRSHLIGHHRVHTGVKPYKCKECGKD 300
301 FSGRTGLIQHQRIHTGEKPYECDECGRPFRVSSALIRHQRIHTANKLY
Interface Residues: 221, 225, 236, 246, 247, 248, 249, 250, 252, 253, 254, 255, 256, 257, 259, 274, 275, 276, 277, 278, 279, 280, 281, 282, 285, 302, 303, 304, 305, 306, 307, 308, 309, 312, 330, 331, 332, 333, 334, 336, 337
3D-footprint Homologues: 7w1m_H, 2kmk_A, 1tf3_A, 7n5w_A, 3uk3_C, 8cuc_F, 7y3l_A, 5kkq_D, 8gn3_A, 2gli_A, 1f2i_J, 1tf6_A, 5ei9_F, 5v3j_F, 8ssq_A, 6blw_A, 5k5i_A, 6u9q_A, 8ssu_A, 8h9h_G, 4m9v_C, 7y3m_I, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 6jnm_A, 5yj3_D, 4x9j_A, 5kl3_A, 2wbs_A, 7txc_E, 1g2f_F, 6ml4_A, 5yel_A, 2drp_D, 2lt7_A, 6a57_A, 1llm_D
Binding Motifs: UN0244.1 aAgTGTTAACAGAGCCTCw
MA2100.1 aAgTGTTAACAGAGCCTC
Publications: ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74 (2012). [Pubmed]
Related annotations: PaperBLAST

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