Transcription Factor
| Accessions: | UP00083A (UniPROBE 20160601) |
| Names: | HMG-box, T-cell specific, Tcf7l2, transcription factor 7-like 2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q924A0 |
| Description: | transcription factor 7-like 2, T-cell specific, HMG-box |
| Length: | 101 |
| Pfam Domains: | 17-85 HMG (high mobility group) box 18-75 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 SKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSR 60 61 EEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQ |
| Interface Residues: | 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 88, 90, 93, 95, 96, 97, 100 |
| 3D-footprint Homologues: | 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 1hry_A |
| Binding Motifs: | UP00083A_1 ddkycCTTTGATstwta UP00083A_2 sdrsWTCAATCrstww |
| Binding Sites: | AATCAAAG ACATCAAA ACTTCAAA ACTTTGAT AGATCAAA AGATCAAT ATCAAAAG ATCAAAGA ATCAAAGC ATCAAAGG CATCAAAG CCTTTGAA CTTCAAAG CTTTGAAC CTTTGATA GATCAAAA GCCTTTGA GGATCAAA TCTTTGAA TGATCAAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.