Transcription Factor

Accessions: Q8N8E2 (JASPAR 2024)
Names: ZN513_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N8E2
Length: 541
Pfam Domains: 150-173 C2H2-type zinc-finger domain
150-172 C2H2-type zinc finger
164-187 Zinc-finger double domain
192-216 Zinc-finger double domain
206-228 C2H2-type zinc finger
206-228 Zinc finger, C2H2 type
206-228 C2H2-type zinc-finger domain
360-382 C2H2-type zinc finger
361-383 C2H2-type zinc-finger domain
374-398 Zinc-finger double domain
388-410 C2H2-type zinc finger
388-410 Zinc finger, C2H2 type
402-426 Zinc-finger double domain
416-438 C2H2-type zinc-finger domain
416-434 C2H2-type zinc finger
416-438 Zinc finger, C2H2 type
430-453 Zinc-finger double domain
444-466 Zinc finger, C2H2 type
444-466 C2H2-type zinc-finger domain
444-466 C2H2-type zinc finger
458-483 Zinc-finger double domain
Sequence:
(in bold interface residues)
1 MPRRKQSHPQPVKCEGVKVDTEDSLDEGPGALVLESDLLLGQDLEFEEEEEEEEGDGNSD 60
61 QLMGFERDSEGDSLGARPGLPYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPAC 120
121 QLCGGPTGEGPCCGAGGPGGGPLLPPRLLYSCRLCTFVSHYSSHLKRHMQTHSGEKPFRC 180
181 GRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHAGPPTPPCPTCG 240
241 FRCCTPRPARPPSPTEQEGAVPRRPEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLC 300
301 GTGSEPLPELLFPWTCRGCGQELEEGEGSRLGAAMCGRCMRGEAGGGASGGPQGPSDKGF 360
361 ACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPL 420
421 CPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYT 480
481 TGHWDNYKRHQKVHGHGGAGGPGLSASEGWAPPHSPPSVLSSRGPPALGTAGSRAVHTDS 540
541 S
Interface Residues: 163, 164, 186, 188, 189, 190, 191, 192, 193, 194, 195, 196, 215, 216, 217, 218, 219, 220, 221, 223, 224, 243, 245, 246, 249, 286, 287, 289, 290, 293, 331, 334, 360, 369, 371, 372, 373, 374, 377, 398, 399, 400, 401, 402, 404, 405, 407, 408, 411, 426, 427, 428, 429, 430, 432, 433, 436, 437, 440, 441, 454, 455, 456, 457, 458, 460, 461, 465, 483, 484, 485, 486, 488, 489
3D-footprint Homologues: 3uk3_C, 8cuc_F, 7y3l_A, 5v3j_F, 5yel_A, 2wbs_A, 4m9v_C, 1tf3_A, 2kmk_A, 2gli_A, 1tf6_A, 6wmi_A, 5ei9_F, 7w1m_H, 7eyi_G, 2i13_A, 6e94_A, 7ysf_A, 8ssu_A, 5kkq_D, 1ubd_C, 8ssq_A, 6ml4_A, 6blw_A, 5und_A, 2drp_D, 2jpa_A, 7n5w_A, 1g2f_F, 5k5i_A, 8gn3_A, 6u9q_A, 4x9j_A, 1mey_C, 5kl3_A, 1f2i_J, 8h9h_G, 2lt7_A, 7y3m_I, 1yuj_A, 6a57_A, 1llm_D, 7txc_E, 5yj3_D, 6jnm_A
Binding Motifs: UN0330.1 rGAGGAAGAr
Binding Sites: UN0330.1.1
UN0330.1.10 / UN0330.1.12
UN0330.1.11 / UN0330.1.13
UN0330.1.12 / UN0330.1.14
UN0330.1.13 / UN0330.1.15
UN0330.1.14
UN0330.1.15
UN0330.1.16
UN0330.1.17
UN0330.1.18
UN0330.1.19
UN0330.1.1 / UN0330.1.2
UN0330.1.17 / UN0330.1.20
UN0330.1.3 / UN0330.1.5
UN0330.1.4 / UN0330.1.6
UN0330.1.5 / UN0330.1.7
UN0330.1.6 / UN0330.1.8
UN0330.1.7 / UN0330.1.9
UN0330.1.10 / UN0330.1.8
UN0330.1.11 / UN0330.1.9
UN0330.1.18
UN0330.1.19
UN0330.1.2
UN0330.1.20
UN0330.1.3
UN0330.1.4
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.