Transcription Factor

Accessions: 6ama_H (3D-footprint 20231221), 6ama_O (3D-footprint 20231221)
Names: F2REK9_STRVP, Putative DNA-binding protein
Organisms: strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745, Streptomyces venezuelae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 55
Pfam Domains: 3-51 Helix-turn-helix domain
5-41 MerR family regulatory protein
6-49 MerR HTH family regulatory protein
Sequence:
(in bold interface residues)
1 EPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQ
Interface Residues: 16, 18, 21, 22, 25, 38
3D-footprint Homologues: 6amk_B, 6ama_L, 5c8e_C, 7tec_A, 5i44_I, 2vz4_A, 2zhg_A
Binding Motifs: 6ama_ABCDGHKLOPY TACCCGnnnTACCCnAnnTACCCnAnnTACCCnnnTTACCCGnnTTACCCGnnnTACCCGnnnTACCCGnnTTACCCGnnnTACCCnnnTTACCCG
Publications: Schumacher MA, den Hengst CD, Bush MJ, Le TBK, Tran NT, Chandra G, Zeng W, Travis B, Brennan RG, Buttner MJ. The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. Nat Commun 9:1139 (2018). [Pubmed]
Related annotations: PaperBLAST

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