Transcription Factor
| Accessions: | Q9BTP6 (JASPAR 2024) |
| Names: | ZBED2_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9BTP6 |
| Length: | 218 |
| Pfam Domains: | 55-107 BED zinc finger |
| Sequence: (in bold interface residues) | 1 MMRREDEEEEGTMMKAKGDLEMKEEEEISETGELVGPFVSAMPTPMPHNKGTRFSEAWEY 60 61 FHLAPARAGHHPNQYATCRLCGRQVSRGPGVNVGTTALWKHLKSMHREELEKSGHGQAGQ 120 121 RQDPRPHGPQLPTGIEGNWGRLLEQVGTMALWASQREKEVLRRERAVEWRERAVEKRERA 180 181 LEEVERAILEMKWKVRAEKEACQREKELPAAVHPFHFV |
| Interface Residues: | 39, 40, 46, 47, 48, 49, 50, 52, 53, 59 |
| 3D-footprint Homologues: | 2w36_A, 6pbd_A |
| Binding Motifs: | MA1971.1 svmmCGAAACCvvv MA1971.2 CGAAACC |
| Binding Sites: | MA1971.1.1 MA1971.1.10 / MA1971.1.20 MA1971.1.11 MA1971.1.12 MA1971.1.13 MA1971.1.14 MA1971.1.15 MA1971.1.16 MA1971.1.17 MA1971.1.18 MA1971.1.19 MA1971.1.2 / MA1971.1.4 MA1971.1.20 MA1971.1.3 / MA1971.1.5 MA1971.1.4 / MA1971.1.6 MA1971.1.10 / MA1971.1.5 MA1971.1.13 / MA1971.1.6 MA1971.1.17 / MA1971.1.7 MA1971.1.18 / MA1971.1.8 MA1971.1.19 / MA1971.1.9 MA1971.1.11 MA1971.1.12 MA1971.1.14 MA1971.1.15 MA1971.1.16 MA1971.1.2 MA1971.1.3 MA1971.1.7 MA1971.1.8 MA1971.1.9 MA1971.2.1 / MA1971.2.12 / MA1971.2.15 / MA1971.2.16 / MA1971.2.17 / MA1971.2.2 / MA1971.2.5 MA1971.2.10 / MA1971.2.19 MA1971.2.11 MA1971.2.13 MA1971.2.14 MA1971.2.18 / MA1971.2.4 / MA1971.2.7 / MA1971.2.9 MA1971.2.20 / MA1971.2.8 MA1971.2.3 MA1971.2.6 |
| Publications: | Somerville TDD, Xu Y, Wu XS, Maia-Silva D, Hur SK, de Almeida LMN, Preall JB, Koo PK, Vakoc CR. ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer. Proc Natl Acad Sci U S A 117:11471-11482 (2020). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.