Transcription Factor

						

			
Accessions: P09016 (JASPAR 2024)

			
Names: Homeobox protein HHO.C13, Homeobox protein Hox-4B, Homeobox protein Hox-5.1, Homeobox protein Hox-D4, HXD4_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P09016
Length: 255
Pfam Domains:   155-211 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQ   60
  61 PFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQ  120
 121 PPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLT  180
 181 RRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQH  240
 241 LQPMAKDHHTDLTTL
Interface Residues: 114, 115, 116, 119, 120, 155, 156, 157, 158, 196, 197, 199, 200, 203, 204, 206, 207, 208, 211
3D-footprint Homologues: 3d1n_M, 1fjl_B, 3cmy_A, 1puf_A, 1ig7_A, 8ejp_B, 6a8r_A, 8pmf_A, 5zfz_A, 1jgg_B, 3lnq_A, 1nk2_P, 1zq3_P, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 6m3d_C, 5flv_I, 2hdd_A, 1b72_A, 5zjt_E, 4cyc_A, 2r5y_A, 8osb_E, 7psx_B, 5hod_A, 2hos_A, 1puf_B, 5jlw_D, 8eml_B, 4xrs_G, 3a01_E, 9b8u_A, 3rkq_B, 8ik5_C, 1le8_A, 2xsd_C, 1e3o_C, 7xrc_C, 8bx1_A, 1mnm_C, 1du0_A, 4qtr_D, 1k61_B, 1o4x_A
Binding Motifs: MA1507.1 rYmATTAr
MA1507.2 YmATTA
			
Publications: Phelan ML, Featherstone MS. Distinct HOX N-terminal arm residues are responsible for specificity of DNA recognition by HOX monomers and HOX. PBX heterodimers 272:8635-43 (J). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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