Transcription Factor
| Accessions: | UP00159A (UniPROBE 20160601) |
| Names: | Homeobox protein SIX2, Sine oculis homeobox homolog 2, sine oculis-related homeobox 2 homolog (Drosophila), Six2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q62232 |
| Description: | sine oculis-related homeobox 2 homolog (Drosophila) |
| Length: | 92 |
| Pfam Domains: | 21-71 Homeobox domain 36-69 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 RVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVS 60 61 NWFKNRRQRDRAAEAKERENSENSNSSSHNPL |
| Interface Residues: | 10, 57, 58, 60, 61, 64, 65, 66, 67, 68, 69, 71, 72, 89 |
| 3D-footprint Homologues: | 4xrs_G, 5jlw_D, 2ld5_A, 1ig7_A, 2xsd_C, 7xrc_C, 4j19_B, 1e3o_C, 7q3o_C, 1au7_A, 1le8_A, 1o4x_A, 4cyc_A, 2d5v_B, 1le8_B, 6es3_K, 1du0_A, 3l1p_A, 1puf_A, 7psx_B, 1jgg_B, 5zfz_A, 3a01_E, 2h1k_B, 8g87_X, 1mnm_C, 6fqp_B, 5flv_I, 3lnq_A, 2lkx_A, 1puf_B, 1k61_B, 5zjt_E, 4qtr_D, 3cmy_A, 2hdd_A, 1nk2_P, 6fqq_E, 1fjl_B, 5hod_A, 3rkq_B, 2r5y_A, 1zq3_P, 6a8r_A, 1b72_A, 4xrm_B, 3d1n_M, 2hos_A, 7t8k_B, 6m3d_C |
| Binding Motifs: | UP00159A_1 rakrGGGTATCAcdwyt |
| Binding Sites: | AATGATAC ACGTATCA AGGGTATC AGGTATCA AGTGATAC ATGATACC ATGATACG ATGATATC CGATACCC CGGTATCA GATACCCC GATATCAC GATATCCC GATGATAC GGATATCA GGTATCAA GGTATCAC TGATACCA TGATATCA GGTGATAC |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.