Transcription Factor

Accessions: UP00016A (UniPROBE 20160601)
Names: MGC129295, sex determining region of Chr Y, Sex-determining region Y protein, Sry, Tdf, Tdy, Testis-determining factor
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q05738
Description: sex determining region of Chr Y
Length: 88
Pfam Domains: 4-72 HMG (high mobility group) box
5-61 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 EGHVKRPMNAFMVWSRGERHKLAQQNPSMQNTEISKQLGCRWKSLTEAEKRPFFQEAQRL 60
61 KILHREKYPNYKYQPHRRAKVSQRSGIL
Interface Residues: 6, 9, 11, 12, 13, 15, 19, 30, 31, 32, 33, 35, 73, 77, 78
3D-footprint Homologues: 4y60_C, 2gzk_A, 1o4x_B, 2lef_A, 3u2b_C, 1qrv_A, 6jrp_D, 3f27_D, 4s2q_D, 7m5w_A, 3tmm_A, 1j5n_A, 3tq6_B, 1hry_A, 1ckt_A, 5oqj_O, 1ytb_A
Binding Motifs: UP00016A_1 khkwATTATAATrwtm
UP00016A_2 yydmdraACAATrrryg
Binding Sites: ATTATAAT
AAAACAAT
AAACAATA
AAACAATT
AACAATAA
AACAATGC
AACAATGG
AACAATGT
AACAATTG
AAGACAAT
AATTGTTA
AATTGTTC
ACAACAAT
AGAACAAT
AGACAATA
ATTGTTAA
ATTGTTCG
ATTGTTTA
CATTGTTA
GAACAATA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.