Transcription Factor
| Accessions: | ZNF415 (SMILE-seq 1.0) |
| Names: | B3KTG1_HUMAN, cDNA FLJ38185 fis, clone FCBBF1000171, highly similar to Homo sapiens zinc finger protein 415, ZNF415 |
| Organisms: | Homo sapiens |
| Libraries: | SMILE-seq 1.0 1 1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Uniprot: | B3KTG1 |
| Notes: | TF family: KRAB+C2H5 |
| Length: | 555 |
| Pfam Domains: | 6-46 KRAB box 236-254 Zinc-finger double domain 244-266 C2H2-type zinc finger 244-266 Zinc finger, C2H2 type 244-254 C2H2-type zinc finger 258-283 Zinc-finger double domain 271-282 C2H2-type zinc finger 272-294 C2H2-type zinc finger 272-294 Zinc finger, C2H2 type 289-311 Zinc-finger double domain 300-322 C2H2-type zinc finger 300-322 Zinc finger, C2H2 type 317-338 Zinc-finger double domain 327-338 C2H2-type zinc finger 328-348 C2H2-type zinc finger 328-350 Zinc finger, C2H2 type 343-366 Zinc-finger double domain 355-376 C2H2-type zinc finger 356-378 C2H2-type zinc finger 356-378 Zinc finger, C2H2 type 371-394 Zinc-finger double domain 383-397 C2H2-type zinc finger 384-406 C2H2-type zinc finger 384-406 Zinc finger, C2H2 type 398-423 Zinc-finger double domain 411-434 C2H2-type zinc finger 412-434 C2H2-type zinc finger 412-434 Zinc finger, C2H2 type 426-450 Zinc-finger double domain 439-458 C2H2-type zinc finger 440-462 Zinc finger, C2H2 type 440-460 C2H2-type zinc finger 454-478 Zinc-finger double domain 467-486 C2H2-type zinc finger 468-488 C2H2-type zinc finger 468-490 Zinc finger, C2H2 type 482-506 Zinc-finger double domain 495-515 C2H2-type zinc finger 496-518 C2H2-type zinc finger 496-518 Zinc finger, C2H2 type 510-534 Zinc-finger double domain 523-543 C2H2-type zinc finger 524-546 C2H2-type zinc finger 524-546 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAFTQLTFRDVAIEFSQDEWKCLNSTQRTLYRDVMLENYRNLVSLDLSRNCVIKELAPQQ 60 61 EGNPGEVFHTVTLEQHEKHDIEEFCFREIKKKIHDFDCQWRDDERNCNKVTTAPKENLTC 120 121 RRDQRDRRGIGNKSIKHQLGLSFLPHPHELQQFQAEGKIYECNHVEKSVNHGSSVSPPQI 180 181 ISSTIKTHVSNKYGTDFICSSLLTQEQKSCIREKPYRYIECDKALNHGSHMTVRQVSHSG 240 241 EKGYKCDLCGKVFSQKSNLARHWRVHTGEKPYKCNECDRSFSRNSCLALHRRVHTGEKPY 300 301 KCYECDKVFSRNSCLALHQKTHIGEKPYTCKECGKAFSVRSTLTNHQVIHSGKKPYKCNE 360 361 CGKVFSQTSSLATHQRIHTGEKPYKCNECGKVFSQTSSLARHWRIHTGEKPYKCNECGKV 420 421 FSYNSHLASHRRVHTGEKPYKCNECGKAFSVHSNLTTHQVIHTGEKPYKCNQCGKGFSVH 480 481 SSLTTHQVIHTGEKPYKCNECGKSFSVRPNLTRHQIIHTGKKPYKCSDCGKSFSVRPNLF 540 541 RHQIIHTKEKPYKRN |
| Interface Residues: | 255, 256, 257, 258, 260, 261, 282, 283, 285, 286, 289, 293, 311, 312, 313, 314, 317, 328, 339, 340, 341, 342, 345, 366, 367, 368, 369, 370, 372, 373, 374, 375, 376, 379, 394, 395, 396, 397, 398, 399, 400, 401, 402, 405, 422, 423, 424, 425, 426, 428, 429, 431, 450, 451, 452, 453, 454, 457, 461, 463, 477, 478, 479, 480, 481, 482, 485, 489, 506, 507, 508, 509, 510, 512, 513, 535, 537, 538, 541 |
| 3D-footprint Homologues: | 5k5i_A, 2drp_D, 7w1m_H, 2gli_A, 8ssu_A, 5kkq_D, 8ssq_A, 5k5l_F, 5yel_A, 5v3j_F, 1ubd_C, 2kmk_A, 7ysf_A, 8cuc_F, 7n5w_A, 6jnm_A, 3uk3_C, 6u9q_A, 1g2f_F, 1llm_D, 6blw_A, 8h9h_G, 4m9v_C, 6e94_A, 7y3m_I, 6a57_A, 2jpa_A, 4x9j_A, 1f2i_J, 2wbs_A, 1tf6_A, 5yj3_D, 5ei9_F, 5kl3_A, 7txc_E, 2lt7_A, 7y3l_A, 1tf3_A, 6ml4_A, 8gn3_A |
| Binding Motifs: | ZNF415 GATmyTaAtcGtGyAb |
| Publications: | Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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