Transcription Factor
Accessions: | 2irf_G (3D-footprint 20231221), 2irf_H (3D-footprint 20231221), 2irf_I (3D-footprint 20231221), 2irf_J (3D-footprint 20231221), 2irf_K (3D-footprint 20231221), 2irf_L (3D-footprint 20231221) |
Names: | INTERFERON REGULATORY FACTOR 2, IRF-2, IRF2_MOUSE |
Organisms: | Mus musculus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P23906 |
Length: | 109 |
Pfam Domains: | 1-109 Interferon regulatory factor transcription factor |
Sequence: (in bold interface residues) | 1 RMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGK 60 61 HQPGIDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKGNNAFRVYRMLP |
Interface Residues: | 36, 38, 71, 75, 76, 78, 79, 82, 83 |
3D-footprint Homologues: | 2pi0_B, 1if1_B, 2o61_A, 2irf_L, 7oot_B |
Binding Motifs: | 2irf_GH AnGTgnAag 2irf_IJKL CtTnCACnTnCnCTTTCACnTnC 2irf_L GTGTA |
Binding Sites: | 2irf_A / 2irf_C 2irf_D / 2irf_F |
Publications: | Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. The EMBO journal 18:5028-41 (1999). [Pubmed] |
Related annotations: | PaperBLAST |
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