Transcription Factor

						

			
Accessions: 2irf_G (3D-footprint 20231221), 2irf_H (3D-footprint 20231221), 2irf_I (3D-footprint 20231221), 2irf_J (3D-footprint 20231221), 2irf_K (3D-footprint 20231221), 2irf_L (3D-footprint 20231221)

			
Names: INTERFERON REGULATORY FACTOR 2, IRF-2, IRF2_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P23906
Length: 109
Pfam Domains:     1-109 Interferon regulatory factor transcription factor
Sequence: 
(in bold interface residues)		   1 RMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGK   60
  61 HQPGIDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKGNNAFRVYRMLP
Interface Residues: 36, 38, 71, 75, 76, 78, 79, 82, 83
3D-footprint Homologues: 2o61_A, 2pi0_B, 1if1_B, 2irf_L, 7oot_B
Binding Motifs: 2irf_GH AnGTgnAag
2irf_IJKL CtTnCACnTnCnCTTTCACnTnC
2irf_L GTGTA
Binding Sites: 2irf_A / 2irf_C
2irf_D / 2irf_F
			
Publications: Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. The EMBO journal 18:5028-41 (1999). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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