Transcription Factor

Accessions: UP00349A (UniPROBE 20160601)
Names: Mig2, MLZ1, Regulatory protein MIG2, YGL209W
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P53035
Description: Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
Length: 118
Pfam Domains: 32-57 Zinc-finger double domain
44-68 C2H2-type zinc finger
45-68 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 PKKQTNFPVDNENRPFRCDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDE 60
61 LKRHMRTHTGQSQRRLKKASVQKQEFLTVSGIPTIASGVMIHQPIPQVLPANMAINVQ
Interface Residues: 26, 27, 28, 29, 30, 32, 33, 34, 56, 57, 58, 59, 60, 61, 62, 63, 64, 67, 82, 85
3D-footprint Homologues: 3uk3_C, 8cuc_F, 2kmk_A, 7y3l_A, 1ubd_C, 5ei9_F, 2jpa_A, 8ssq_A, 1mey_C, 7w1m_H, 6jnm_A, 5und_A, 2drp_D, 1f2i_J, 7eyi_G, 6a57_A, 5k5i_A, 8ssu_A, 6ml4_A, 5v3j_F, 1g2f_F, 7n5w_A, 6blw_A, 5kkq_D, 2lt7_A, 6u9q_A, 5yel_A, 4x9j_A, 2i13_A, 8h9h_G, 1llm_D, 7txc_E, 5kl3_A, 4m9v_C, 7ysf_A, 6wmi_A, 1tf3_A, 1tf6_A, 7y3m_I, 6e94_A, 8gn3_A, 2wbs_A, 5yj3_D, 2gli_A
Binding Motifs: UP00349A_1 wyrwryTACCCCGCAwTtwrk
Binding Sites: AACCCCGC
ACCCCACA
ACCCCGCA
ACCCCGCC
ACCCCGCG
ATGCGGGG
ATGTGGGG
CACCCCGC
CCCCACAA
CCCCACAC
CCCCCGCA
CCCCGCAA
CCCCGCAC
CCCCGCAG
GCCCCGCA
GCGGGGAA
GCGGGGTA
GTGGGGTA
TCCCCACA
TCCCCGCA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.