Transcription Factor

Accessions: 6cg0_N (3D-footprint 20231221)
Names: High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 75
Pfam Domains: 1-33 Domain of unknown function (DUF1898)
32-72 Domain of unknown function (DUF1898)
33-73 HMG (high mobility group) box
Sequence:
(in bold interface residues)
1 SYAFFVQTCREEHKKKSVNFSEFSKKCSERWKKRPPSAFFLFCSEYRPKIKGEHPGLSIG 60
61 DVAKKLGEMWNNTAA
Interface Residues: 2, 6, 20, 22, 24, 26, 29, 34, 37, 39, 40, 43, 47, 58, 59, 60, 63
3D-footprint Homologues: 1ckt_A, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 3tq6_B, 1hry_A
Binding Motifs: 6cg0_CN ACnnnnnnnnnnnncAAGTnnnnannnAG
6cg0_N CTnnnnnnnnaCTt
Binding Sites: 6cg0_G
6cg0_M
Publications: Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. Cracking the DNA Code for V(D)J Recombination. Mol Cell 70:358-370 (2018). [Pubmed]
Related annotations: PaperBLAST

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