Transcription Factor

						

			
Accessions: 3co7_F (3D-footprint 20231221), 3coa_F (3D-footprint 20231221)

			
Names: Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, FOXO1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q12778
Length: 87
Pfam Domains:      9-87 Fork head domain
Sequence: 
(in bold interface residues)		   1 SRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIR   60
  61 HNLSLHSKFIRVQNEGTGKSSWWMLNP
Interface Residues: 51, 54, 56, 57, 58, 60, 61, 62, 64, 65, 74, 79
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 3qrf_G
Binding Motifs: 3co7_F TgtTTA
3coa_F TgTTTt
Binding Sites: 3coa_D
3coa_E
3co7_A
3co7_B
			
Publications: Brent M.M, Anand R, Marmorstein R. Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure (London, England : 1993) 16:1407-16 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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