Transcription Factor

						

			
Accessions: 3wty_C (3D-footprint 20231221)

			
Names: ETS1_HUMAN, p54, Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P14921
Length: 118
Pfam Domains:     17-98 Ets-domain
Sequence: 
(in bold interface residues)		   1 PVIPAAALAGYTGSPPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKR   60
  61 KNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK
Interface Residues: 14, 47, 51, 52, 55, 69, 70, 72, 73, 74, 76, 77, 91
3D-footprint Homologues: 3zp5_A, 2wbs_A, 8ee9_F, 4mhg_A, 1dux_F, 4uno_A, 3jtg_A, 7jsa_J, 2stt_A, 4bqa_A, 1bc8_C, 4iri_A, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B
Binding Motifs: 3wty_AC GCCACATCCT
Binding Sites: 3wty_D
3wty_E
			
Publications: Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K. A Novel Allosteric Mechanism on Protein-DNA Interactions underlying the Phosphorylation-Dependent Regulation of Ets1 Target Gene Expressions. Journal of molecular biology 427:1655-69 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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