Transcription Factor

						

			
Accessions: VENTX_DBD (HumanTF 1.0)

			
Names: Homeobox protein VENTX, VENT homeobox homolog, VENT-like homeobox protein 2, VENTX, VENTX_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: O95231
Notes: Ensembl ID: ENSG00000151650; DNA-binding domain sequence; TF family: homeodomain; Clone source: Gene synthesis
Length: 111
Pfam Domains:     26-81 Homeobox domain
Sequence: 
(in bold interface residues)		   1 GSSNLPAPERTMAGLSKEPNTLRAPRVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLARE   60
  61 MQLSEVQIKTWFQNRRMKHKRQMQDPQLHSPFSGSLHAPPAFYSTSSGLAN
Interface Residues: 23, 24, 25, 26, 27, 28, 66, 67, 69, 70, 73, 74, 76, 77, 78, 81
3D-footprint Homologues: 3d1n_M, 1nk2_P, 8ejp_B, 1zq3_P, 3rkq_B, 2lkx_A, 1jgg_B, 6m3d_C, 3lnq_A, 7q3o_C, 6es3_K, 1fjl_B, 5zjt_E, 3a01_E, 8ik5_C, 7psx_B, 1b72_A, 5hod_A, 1ig7_A, 6a8r_A, 3cmy_A, 2hdd_A, 8osb_E, 5jlw_D, 4cyc_A, 2r5y_A, 1puf_A, 8eml_B, 4xrs_G, 2hos_A, 8pmf_A, 5zfz_A, 4j19_B, 1puf_B, 1au7_A, 5flv_I, 2ld5_A, 9b8u_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 8bx1_A, 4qtr_D, 1o4x_A, 4xrm_B, 1le8_B, 1du0_A, 1mnm_C, 8g87_X, 1k61_B
Binding Motifs: VENTX_DBD_1 AmCrATTAr
VENTX_DBD_2 csyTAATsGrWAAaCGATTAG
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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