Transcription Factor
| Accessions: | UP00334A (UniPROBE 20160601) |
| Names: | CAR80, CARGR1, Negative transcriptional regulator of IME2, NIM2, RIM16, Transcriptional regulator UME6, Ume6, YD8142.04C, YDR207C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P39001 |
| Description: | Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms comp... |
| Length: | 118 |
| Pfam Domains: | 51-85 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 KGKNVKPKAKSKAKQSSKKRPNNTTSKSKANNSQESNNATSSTSQGTRSRTGCWICRLRK 60 61 KKCTEERPHCFNCERLKLDCHYDAFKPDFVSDPKKKQMKLEEIKKKTKEAKRRAMKKK |
| Interface Residues: | 59, 60, 61, 104 |
| 3D-footprint Homologues: | 1pyi_A, 1hwt_C, 7uik_T, 3coq_A, 1d66_B, 6gys_C, 3qex_A |
| Binding Motifs: | UP00334A_1 httwwcGGCGGCwAwwtcka |
| Binding Sites: | AGCCGCCA AGCCGCCG AGCCGCGG AGCGGCTA ATAGCCGC ATTGCCGC CGCGGCTA CGGCGGCA GCCGCCAA GCGGCAAA GCGGCTAA GCGGTTAA GGCGCTTA GGCGGCAA GGCGGCTA GGCGGTTA GGGCGGCA AGCCGCCT CGCGGTTA GGCGGGTA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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