Transcription Factor

						

			
Accessions: ZNF296 (HT-SELEX2 May2017)

			
Names: ENSG00000170684, ZNF296
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: Znf_C2H2 experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 338
Pfam Domains:     22-38 C2H2-type zinc finger
   95-116 Zinc finger, C2H2 type
   96-116 C2H2-type zinc finger
  108-132 Zinc-finger double domain
  122-144 C2H2-type zinc finger
  250-271 Zinc finger, C2H2 type
  251-271 C2H2-type zinc finger
  263-287 Zinc-finger double domain
  308-331 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 QLFRGPSRGQGSEREELKALSCLRCGKQFTVAWKLLRHAQWDHGLSIYQTESEAPEAPLL   60
  61 GLAEVAAAVSAVVGPAAEAKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMRSHTGER  120
 121 PYACDQCPYACAQSSKLNRHKKTHRQVPPQSPLMADTSQEQASAAPPEPAVHAAAPTSTL  180
 181 PCSGGEGAGAAATAGVQEPGAPGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKS  240
 241 GGKSRGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMHG  300
 301 MTPGSTRFECPHCHVPFGLRATLDKHLRQKHPEAAGEA
Interface Residues: 80, 83, 104, 105, 106, 107, 108, 110, 111, 133, 134, 135, 136, 139, 165, 167, 168, 171, 188, 191, 192, 194, 214, 217, 220, 222, 223, 224, 225, 228, 230, 231, 232, 233, 236, 240, 259, 260, 261, 262, 263, 265, 266, 267, 268, 269, 272, 273, 274, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 298, 318, 319, 320, 321, 322, 323, 324, 325, 329
3D-footprint Homologues: 8h9h_G, 7n5w_A, 1g2f_F, 7y3l_A, 5v3j_F, 7w1m_H, 4x9j_A, 2gli_A, 8ssq_A, 8ssu_A, 8gn3_A, 2lt7_A, 5yj3_D, 1tf6_A, 1tf3_A, 6ml4_A, 8cuc_F, 6jnm_A, 3uk3_C, 2kmk_A, 7ysf_A, 2drp_D, 1f2i_J, 6blw_A, 6u9q_A, 5kkq_D, 1ubd_C, 5ei9_F, 1llm_D, 5kl3_A, 7txc_E, 5k5i_A, 4m9v_C, 6e94_A, 8gh6_A, 7y3m_I, 6a57_A, 2jpa_A, 1yuj_A, 5yel_A, 2wbs_A, 5k5l_F
Binding Motifs: ZNF296_2 brsTGGwCAbt
ZNF296_methyl_1 trsTGGwCrbt
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.