Transcription Factor

						

			
Accessions: Q61575 (JASPAR 2024)

			
Names: Forkhead box protein N1, FOXN1_MOUSE, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/forkhead homolog 11, Winged-helix transcription factor nude
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 648
Pfam Domains:   271-361 Fork head domain
Sequence: 
(in bold interface residues)		   1 MVSLLPPQSDVTLPGSTRLEGEPQGDLMQAPGLPDSPAPQNKHANFSCSSFVPDGPPERT   60
  61 PSLPPHSPSIASPDPEQIQGHCTAGPGPGSFRLSPSEKYPGFGFEEGPAGSPGRFLKGNH  120
 121 MPFHPYKRHFHEDIFSEAQTAMALDGHSFKTQGALEAFEEIPVDMGDAEAFLPSFPAEAW  180
 181 CNKLPYPSQEHNQILQGSEVKVKPQALDSGPGMYCYQPPLQHMYCSSQPAFHQYSPGGGS  240
 241 YPVPYLGSPHYPYQRIAPQANAEGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNF  300
 301 MTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPSKIDKMQEEL  360
 361 QKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLAGPGPIRPMAPSAGLS  420
 421 QPLHPMHPAPGPMPGKNPLQDLLGGHAPSCYGQTYPHLSPSLAPSGHQQPLFPQPDGHLE  480
 481 LQAQPGTPQDSPLPAHTPPSHGAKLMAEPSSARTMHDTLLPDGDLGTDLDAINPSLTDFD  540
 541 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMLPPPPAAHCFPPGPCLAETGNEAGELAPP  600
 601 GSGGSGALGDMHLSTLYSAFVELESTPSSAAAGPAVYLSPGSKPLALA
Interface Residues: 294, 313, 314, 316, 317, 318, 320, 321, 322, 324, 325, 334, 342
3D-footprint Homologues: 8vfz_O, 8bzm_E, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 8sro_B, 3qrf_G
Binding Motifs: MA1684.1 rGAmGC
			
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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