Transcription Factor

Accessions: T090223_1.02 (CISBP 1.02), P92953 (JASPAR 2024)
Names: ATHB-4, T090223_1.02;, ATHB4_ARATH, HD-ZIP protein ATHB-4, Homeobox-leucine zipper protein ATHB-4, Homeodomain transcription factor ATHB-4
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 318
Pfam Domains: 1-125 HD-ZIP protein N terminus
162-216 Homeobox domain
218-261 Homeobox associated leucine zipper
Sequence:
(in bold interface residues)
1 MGERDDGLGLSLSLGNSQQKEPSLRLNLMPLTTSSSSSSFQHMHNQNNNSHPQKIHNISW 60
61 THLFQSSGIKRTTAERNSDAGSFLRGFNVNRAQSSVAVVDLEEEAAVVSSPNSAVSSLSG 120
121 NKRDLAVARGGDENEAERASCSRGGGSGGSDDEDGGNGDGSRKKLRLSKDQALVLEETFK 180
181 EHSTLNPKQKLALAKQLNLRARQVEVWFQNRRARTKLKQTEVDCEYLKRCCDNLTEENRR 240
241 LQKEVSELRALKLSPHLYMHMTPPTTLTMCPSCERVSSSAATVTAAPSTTTTPTVVGRPS 300
301 PQRLTPWTAISLQQKSGR
Interface Residues: 161, 162, 163, 164, 165, 202, 203, 205, 206, 209, 210, 212, 213, 214, 216, 217
3D-footprint Homologues: 5zfz_A, 3d1n_M, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 2r5y_A, 1puf_A, 7psx_B, 8ejp_B, 6a8r_A, 1puf_B, 8osb_E, 8eml_B, 3rkq_B, 5flv_I, 9b8u_A, 5zjt_E, 8ik5_C, 5jlw_D, 1e3o_C, 1le8_A, 1au7_A, 2xsd_C, 7q3o_C, 1ig7_A, 7xrc_C, 5hod_A, 4qtr_D, 1fjl_B, 3lnq_A, 1b72_A, 6es3_K, 4xrs_G, 3a01_E, 8pmf_A, 1o4x_A, 8g87_X, 1du0_A, 3cmy_A, 2hdd_A, 1jgg_B, 8bx1_A, 4cyc_A, 2hos_A, 6m3d_C
Binding Motifs: M0845_1.02 syAATcAttr
MA1406.1 yAATsATTGs
MA1406.2 yAATsATTG
Publications: Johannesson H., Wang Y., Engstrom P. DNA-binding and dimerization preferences of Arabidopsis homeodomain-leucine zipper transcription factors in vitro. Plant Mol. Biol. 45:63-73 (2001). [Pubmed]
Related annotations: PaperBLAST

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