Transcription Factor

						

			
Accessions: T081593_1.02 (CISBP 1.02)

			
Names: FOXA2, T081593_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Forkhead
Length: 343
Pfam Domains:     20-44 Forkhead N-terminal region
   45-140 Fork head domain
  259-332 HNF3 C-terminal domain
Sequence: 
(in bold interface residues)		   1 MLGAVKMEGHEPSDWSSYYAEPEGYSSLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQ   60
  61 SPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT  120
 121 LHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPA  180
 181 SETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPH  240
 241 HPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGY  300
 301 GSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
Interface Residues: 35, 37, 39, 40, 42, 68, 87, 88, 90, 91, 92, 94, 95, 96, 98, 99, 108, 115, 136, 140
3D-footprint Homologues: 7yz7_A, 7yzb_A, 8vfz_O, 8bzm_E, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 3l2c_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 8sro_B, 3qrf_G
Binding Motifs: M3411_1.02 wAAryAAAyAwtwmm
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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