Transcription Factor

Accessions: 6omf_F (3D-footprint 20231221)
Names: RNA polymerase sigma factor RpoS, S5ZIY8_SALTM, Sigma S, Sigma-38
Organisms: Salmonella enterica subsp. enterica serovar Typhimurium
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: S5ZIY8
Length: 278
Pfam Domains: 5-38 Sigma-70 factor, region 1.2
43-113 Sigma-70 region 2
123-198 Sigma-70 region 3
211-264 Sigma-70, region 4
Sequence:
(in bold interface residues)
1 QRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGN 60
61 RGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHI 120
121 VKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNERITSVDTPLGGDSE 180
181 KALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDV 240
241 GREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFR
Interface Residues: 237, 238, 247, 248, 249, 250, 252, 253
3D-footprint Homologues: 3n97_A, 6ido_B, 8cyf_B, 6wpa_A
Binding Motifs: 6omf_F TAACgnGAGCAnCnnnnnnnnnnnncGcT
Binding Sites: 6omf_N
6omf_T
Publications: Cartagena AJ, Banta AB, Sathyan N, Ross W, Gourse RL, Campbell EA, Darst SA. Structural basis for transcription activation by Crl through tethering of σ(S) and RNA polymerase. Proc Natl Acad Sci U S A 116:18923-18927 (2019). [Pubmed]
Related annotations: PaperBLAST

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