Transcription Factor

						

			
Accessions: 5c8e_A (3D-footprint 20231221)

			
Names: Light-dependent transcriptional regulator CarH, Q746J7_THET2
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q746J7
Length: 273
Pfam Domains:      3-71 MerR HTH family regulatory protein
     4-41 MerR family regulatory protein
   80-152 B12 binding domain
Sequence: 
(in bold interface residues)		   1 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGA   60
  61 TPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVL  120
 121 REVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLA  180
 181 AYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRV  240
 241 FLGGQGAGPEEARRLGAEYMEDLKGLAEALWLP
Interface Residues: 17, 20, 21, 24, 25, 38
3D-footprint Homologues: 7tec_A, 5c8e_C, 6ldi_G, 1r8d_B, 5d8c_A, 6xh7_H, 4r24_B, 5i44_I, 7tea_B, 4r4e_B, 6jgx_B
Binding Motifs: 5c8e_AF TGTAnnT
			
Publications: Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, Elías-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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