Transcription Factor

Accessions: 2c7a_A (3D-footprint 20231221)
Names: Nuclear receptor subfamily 3 group C member 3, PRGR_HUMAN, PROGESTERONE RECEPTOR
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P06401
Length: 78
Pfam Domains: 4-71 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 PQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPAC 60
61 RLRKCCQAGMVLGGRKFK
Interface Residues: 13, 14, 16, 17, 23, 24, 26, 27, 30, 31, 55, 77
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B
Binding Motifs: 2c7a_AB CaGnaCAnnnTGTnCng
Publications: Roemer S.C, Donham D.C, Sherman L, Pon V.H, Edwards D.P, Churchill M.E. Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements. Molecular endocrinology (Baltimore, Md.) 20:3042-52 (2006). [Pubmed]
Related annotations: PaperBLAST

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