Transcription Factor

Accessions: Q4H3K3 (JASPAR 2024)
Names: Q4H3K3_CIOIN
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H3K3
Length: 572
Pfam Domains: 206-285 Sterile alpha motif (SAM)/Pointed domain
331-413 Ets-domain
Sequence:
(in bold interface residues)
1 MQQHISATADCLSRGPHKPQIHPHNSSLASNDSNPVALPSVSGAIWARPNNRVNAQLPAD 60
61 SRPSIGKTIDPSHTMHYDSSKSFSTFHYPDTTSRLNYGQHSHCTYSSPTAPVTWFDPKLS 120
121 TAVQSDGNSHLNQGVKQRTRNRSTLPVDYSRKRSLSVTTPHNETPTPRKRRSLGSVAGHF 180
181 DKMALGAENAATMDSGRKVQTSDHHDTKELEVFVPSELSSWTNSHVVQWLTWVVHEYKLQ 240
241 KVDCSRFKGITGIDLSKMTVKDFKNLTSTEKDADVFFSHLQYLKGNRKPASPKAGNGAKT 300
301 KSGQALSSKLEDTYTLLGPLCTKLSKQGGGQIQLWQFLLELLSDPANATCITWEGTSGEF 360
361 KMVDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLAQAI 420
421 QITNSPERFGYTYGQTPAGLPSYNEAIHQINMIQPLMDDKTTPWFAAVGRHVATSGGAND 480
481 YLTNTFGGATGYFSQTAEIPHEHHSSPYSISSHIQSRPYYHQYSSNFYPNQDYQSSPNYY 540
541 PYYNRTHSGPMSMQLTYNSSLDSGVTNQIGMY
Interface Residues: 384, 385, 387, 388, 389, 391, 392, 406
3D-footprint Homologues: 3jtg_A, 1dux_F, 8ee9_F, 3zp5_A, 4mhg_A, 8smh_F, 4uno_A, 2stt_A, 8smj_F, 7jsa_J, 4lg0_B, 1yo5_C, 4iri_A, 1awc_A, 4l18_B, 1bc8_C
Binding Motifs: MA1856.1 rdyybyryTTCCGGtttbggkk
MA1856.2 ryTTCCGGt
Publications: Khoueiry P, Rothbächer U, Ohtsuka Y, Daian F, Frangulian E, Roure A, Dubchak I, Lemaire P. A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites. Curr Biol 20:792-802 (2010). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.