Transcription Factor

						

			
Accessions: 3brf_A (3D-footprint 20231221)

			
Names: Lin-12 and glp-1 phenotype protein 1, isoform a
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9TYY1
Length: 423
Pfam Domains:    21-145 LAG1, DNA binding
  150-299 Beta-trefoil DNA-binding domain
  340-421 IPT/TIG domain
Sequence: 
(in bold interface residues)		   1 SLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIGQGWKLKKDRV   60
  61 AQLYKTLTELVAYIGIGSDTSERQQLDFPNIYDYCAAKTLYISDSDKRKYFDLNAQFFYG  120
 121 CGMEIGGFVSQRIKVISKPSKKKQSDCKYLCIASGTKVALFNRLRSQTVSTRYLHVEGNA  180
 181 FHASSTKWGAFTIHLFDDEQETDNFAVRDGFVYYGSVVKLVDSVTGIALPRLRIRKVDKQ  240
 241 QVILDASCSEEPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAINEHRHQINDGAAWT  300
 301 IISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGRDFKPNLKVWFGAT  360
 361 PVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVEVPISLVRDDGVVYSSGLTFS  420
 421 YKS
Interface Residues: 33, 36, 38, 137, 138, 141, 165, 166, 167
3D-footprint Homologues: 3iag_C, 5e24_E, 3brd_A
Binding Motifs: 3brf_A TGTGGGAA
Binding Sites: 3brf_B
3brf_C
			
Publications: Friedmann D.R, Wilson J.J, Kovall R.A. RAM-induced allostery facilitates assembly of a notch pathway active transcription complex. The Journal of biological chemistry 283:14781-91 (2008). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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