Transcription Factor

						

			
Accessions: 2e1c_A (3D-footprint 20231221)

			
Names: Feast/famine regulatory protein FL11, FFRP FL11, HTH-type transcriptional regulator FL11, Putative HTH-type transcriptional regulator PH1519, REG6_PYRHO
Organisms: Pyrococcus horikoshii, strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O59188
Length: 147
Pfam Domains:      2-49 Winged helix-turn-helix DNA-binding
     2-43 AsnC-type helix-turn-helix domain
     8-50 Bacterial regulatory protein, arsR family
   68-138 AsnC family
Sequence: 
(in bold interface residues)		   1 PLDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEAL   60
  61 GYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDL  120
 121 IGSIPGVEGTHTMIVLKTHKETTELPI
Interface Residues: 21, 31, 32, 33, 34, 36, 37, 40
3D-footprint Homologues: 2e1c_A, 4hf1_A, 4lb5_B
Binding Motifs: 2e1c_A TTTCA
Binding Sites: 2e1c_B
2e1c_D
			
Publications: Yokoyama K, Ishijima S.A, Koike H, Kurihara C, Shimowasa A, Kabasawa M, Kawashima T, Suzuki M. Feast/famine regulation by transcription factor FL11 for the survival of the hyperthermophilic archaeon Pyrococcus OT3. Structure (London, England : 1993) 15:1542-54 (2007). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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