Transcription Factor

Accessions: 5yj3_D (3D-footprint 20231221)
Names: hKR3, Krueppel-related zinc finger protein 3, Telomere zinc finger-associated protein, TZAP_HUMAN, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 66
Pfam Domains: 3-21 Zinc-finger of C2H2 type
3-24 Zinc finger, C2H2 type
3-24 C2H2 type zinc-finger (2 copies)
4-24 C2H2-type zinc finger
17-41 Zinc-finger double domain
28-52 C2H2 type zinc-finger (2 copies)
30-50 Zinc-finger of C2H2 type
30-52 C2H2-type zinc finger
30-52 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 PHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNP 60
61 RQRKLR
Interface Residues: 12, 13, 14, 15, 16, 17, 18, 19, 20, 40, 41, 42, 43, 44, 45, 46, 47, 48, 51, 63, 66
3D-footprint Homologues: 5ei9_F, 7w1m_H, 3uk3_C, 8cuc_F, 1tf3_A, 7y3l_A, 1g2f_F, 5yel_A, 4x9j_A, 2i13_A, 8gn3_A, 1llm_D, 7txc_E, 5kl3_A, 2wbs_A, 1ubd_C, 2jpa_A, 8h9h_G, 1mey_C, 6jnm_A, 5und_A, 2drp_D, 1f2i_J, 6a57_A, 5k5i_A, 2kmk_A, 8ssq_A, 6ml4_A, 2gli_A, 7n5w_A, 6blw_A, 5kkq_D, 2lt7_A, 8ssu_A, 1tf6_A, 6u9q_A, 4m9v_C, 6e94_A, 7ysf_A, 6wmi_A, 7eyi_G, 8gh6_A, 7y3m_I, 5yj3_D, 5v3j_F
Binding Motifs: 5yj3_CD tTAGGGtTAG
5yj3_D rCCCTAr
Binding Sites: 5yj3_A
5yj3_B
Publications: Zhao Y, Zhang G, He C, Mei Y, Shi Y, Li F. The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA. Cell Res 28:130-134 (2018). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.