Transcription Factor

Accessions: UP00323A (UniPROBE 20160601)
Names: Not Available, Ydr520c
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Not Av
Description: Putative transcription factor; contains the (Zn(II)2Cys6 motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and sensitive to caffeine
Length: 142
Pfam Domains: 52-88 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 AGYNSASGKVRNSIRSIINHPEDSARAKERSETNSPKNNGNKKPRKKRKTFSCDTCRRVK 60
61 TRCDFEPFIGKCYRCNVLQLDCSLARNKDNEILNTLREDGLLKKINSINHNLGSFSHLNA 120
121 DSPNESQSSFEKNGTVNFDNYM
Interface Residues: 46, 47, 57, 59, 60, 61, 62
3D-footprint Homologues: 1f5e_P, 1hwt_C
Binding Motifs: UP00323A_1 wmvcdyCGGAGATAwtkdkm
Binding Sites: AATCTCCG
ACGGAGAA
ACGGAGAT
ATCTCCGA
ATCTCCGG
ATTCTCCG
ATTTCCGG
ATTTTCCG
CCGGAGAA
CGGAAATA
CGGAATTA
CGGACATA
CGGACTTA
CGGAGAAA
CGGAGATA
CGGAGTTA
CGGATTTA
CGGGGATA
GGAGATAA
TCGGAGAA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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