Transcription Factor
| Accessions: | T095232_1.02 (CISBP 1.02), Q7TNE6 (JASPAR 2024) |
| Names: | Duxbl, T095232_1.02;, Double homeobox B-like, Double homeobox B-like 1, Double homeodomain protein, Q7TNE6_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 350 |
| Pfam Domains: | 15-70 Homeobox domain 95-149 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MELSCSTGLLEKEARRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMT 60 61 WFQKHRKIRKQAEFACCSEESQEQEQDKPRVKEARRSRTHFTKFQTDILIEAFEKNRFPG 120 121 IVTREKLAQQTGIPESRIHIWFQNRRARHPDPGQNTQKTPHPPQSSQGPTQKTVGKLAPS 180 181 KTLTSSASVILPLSPPHTPNGPLDLSKGRQKQLPGTTLLQSSQVVQQRSDDQNPNKGHLS 240 241 PTTTPGEQGFHSQPPLQLLTQNRGHNPRESGGLAVPRLEDCTQVPAVNQHFRKLDQNDSS 300 301 FLQHWDEWFGSMLAEWMPDKEYWSEKAELHPWQVQLRQLASVSPQAHQTP |
| Interface Residues: | 18, 54, 55, 56, 57, 59, 60, 63, 64, 66, 67, 95, 96, 97, 98, 103, 136, 137, 139, 140, 143, 144, 147, 148 |
| 3D-footprint Homologues: | 8ik5_C, 2h8r_B, 8g87_X, 8bx1_A, 8pmf_A, 8ejp_B, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 8eml_B, 4cyc_A, 2hos_A, 2d5v_B, 9b8u_A, 8osb_E, 7psx_B, 8pi8_B |
| Binding Motifs: | M1038_1.02 myyaATCAr UN0671.1 yyTAAyCYAATCAArwyw UN0671.2 yTAAyCYAATCAA |
| Binding Sites: | UN0671.1.1 UN0671.1.10 / UN0671.1.14 UN0671.1.11 / UN0671.1.15 UN0671.1.12 / UN0671.1.16 UN0671.1.13 / UN0671.1.17 UN0671.1.14 / UN0671.1.18 UN0671.1.15 / UN0671.1.20 UN0671.1.16 UN0671.1.17 UN0671.1.18 UN0671.1.19 UN0671.1.2 UN0671.1.20 UN0671.1.3 UN0671.1.4 / UN0671.1.6 UN0671.1.5 / UN0671.1.7 UN0671.1.6 / UN0671.1.9 UN0671.1.10 / UN0671.1.7 UN0671.1.11 / UN0671.1.8 UN0671.1.12 / UN0671.1.9 UN0671.1.13 UN0671.1.19 UN0671.1.4 UN0671.1.5 UN0671.1.8 UN0671.2.1 UN0671.2.10 / UN0671.2.15 / UN0671.2.2 UN0671.2.11 UN0671.2.12 UN0671.2.13 UN0671.2.14 / UN0671.2.20 / UN0671.2.9 UN0671.2.16 / UN0671.2.5 UN0671.2.17 UN0671.2.18 UN0671.2.19 UN0671.2.3 UN0671.2.4 UN0671.2.6 UN0671.2.7 UN0671.2.8 |
| Related annotations: | PaperBLAST |
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