Transcription Factor
| Accessions: | T (HT-SELEX2 May2017) |
| Names: | ENSG00000164458, T |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: T_box experiment: HT-SELEX Hamming distance: 2 cycle: 4, TF family: T_box experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 4 |
| Length: | 221 |
| Pfam Domains: | 21-196 T-box |
| Sequence: (in bold interface residues) | 1 VENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLD 60 61 PNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSF 120 121 SKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEI 180 181 TALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPGYSQW |
| Interface Residues: | 46, 173, 174, 190, 193, 194 |
| 3D-footprint Homologues: | 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B, 2x6v_A |
| Binding Motifs: | T_3 rAsGTGyGAaawtTcrCACCTy T_4 tTCRCACcTAgGTGyGAa T_methyl_1 rAsGTGyGAaAwkTcrCACcTy T_methyl_2 tTcrCACsTAsGTGygAa |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.