Transcription Factor
| Accessions: | UP00199A (UniPROBE 20160601) |
| Names: | AI047561, Arec3, Homeobox protein SIX4, Sine oculis homeobox homolog 4, sine oculis-related homeobox 4 homolog (Drosophila), Six4, Skeletal muscle-specific ARE binding protein AREC3, TrexBF |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q61321 |
| Description: | sine oculis-related homeobox 4 homolog (Drosophila) |
| Length: | 93 |
| Pfam Domains: | 22-73 Homeobox domain 38-70 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 YRLRRKFPLPRTIWDGEETVYCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQV 60 61 SNWFKNRRQRDRNPSETQSKSESDGNPSTEDES |
| Interface Residues: | 11, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73 |
| 3D-footprint Homologues: | 4xrs_G, 5jlw_D, 2ld5_A, 1le8_A, 1ig7_A, 2xsd_C, 7q3o_C, 6ryd_F, 4j19_B, 7xrc_C, 1e3o_C, 1au7_A, 1zq3_P, 7psx_B, 6a8r_A, 1b72_A, 4xrm_B, 3d1n_M, 1o4x_A, 4cyc_A, 2d5v_B, 1le8_B, 6es3_K, 1du0_A, 3l1p_A, 1puf_A, 1jgg_B, 5zfz_A, 3a01_E, 2h1k_B, 1mnm_C, 6fqp_B, 5flv_I, 3lnq_A, 2lkx_A, 1puf_B, 6wig_A, 1k61_B, 5zjt_E, 4qtr_D, 3cmy_A, 2hdd_A, 8g87_X, 1nk2_P, 6fqq_E, 1fjl_B, 5hod_A, 3rkq_B, 2r5y_A, 2hos_A, 6m3d_C |
| Binding Motifs: | UP00199A_1 atrmaTGACACCthybr |
| Binding Sites: | AGATATCA AGGGATCA AGGTATCA AGGTGTCA AGTATCAT ATGATACC ATGATACG ATGATATC CGGTGTCA CTGACACC GATACCCC GGGTATCA GGGTGTCA GGTATCAA GGTATCAC GGTGTCAA GGTGTCAC GTATCATA TGACACCA TGATATCA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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