Transcription Factor
| Accessions: | UP00040A (UniPROBE 20160601) |
| Names: | AW491843, interferon regulatory factor 5, IRF-5, Irf5, mirf5 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P56477 |
| Description: | interferon regulatory factor 5 |
| Length: | 137 |
| Pfam Domains: | 13-121 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 NHSAPGIPPPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFYIPWRHATRHGPSQDGDN 60 61 TIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFQLFYDGPRDMPPQPYKIYEVC 120 121 SNGPAPTESQPTDDYVL |
| Interface Residues: | 48, 50, 83, 87, 88, 90, 91, 94, 95 |
| 3D-footprint Homologues: | 2pi0_B, 1if1_B, 2o61_A, 2irf_L, 7oot_B |
| Binding Motifs: | UP00040A_1 wwrwAyCGAAACyaa UP00040A_2 ttrAyCGAGArttcs |
| Binding Sites: | AACGAAAC AAGTTTCG ACCGAAAC ACGAAACC AGCGAAAC AGGTTTCG AGTTTCGA AGTTTCGC AGTTTCGG ATCGAAAC ATCGATAC CAGTTTCG CCGAAACC CGAAACCA CGAAACCG CGAAACTA CGAAACTC CGATACCA GCGAAACC GGTTTCGA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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