Transcription Factor
| Accessions: | ap (DrosophilaTF 1.1), P29673 (JASPAR 2024) |
| Names: | APTE_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 469 |
| Pfam Domains: | 148-203 LIM domain 210-265 LIM domain 368-424 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MGVCTEERPVMHWQQSARFLGPGAREKSPTPPVAHQGSNQCGSAAGANNNHPLFRACSSS 60 61 SCPDICDHSTKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSDETTSGI 120 121 SFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQ 180 181 PLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTV 240 241 CHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSD 300 301 PSRSIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDLNTEYVDFGRGSH 360 361 LSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARA 420 421 KWRRMMMKQDGSGLLEKGEGALDLDSISVHSPTSFILGGPNSTPPLNLD |
| Interface Residues: | 368, 369, 370, 371, 409, 410, 412, 413, 416, 417, 420, 421, 423, 424 |
| 3D-footprint Homologues: | 3d1n_M, 1fjl_B, 6a8r_A, 2h1k_B, 1ig7_A, 1puf_A, 3cmy_A, 5zfz_A, 1zq3_P, 6m3d_C, 1nk2_P, 3lnq_A, 2lkx_A, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 5zjt_E, 4cyc_A, 2d5v_B, 7psx_B, 5hod_A, 3l1p_A, 1b72_A, 3a01_E, 5jlw_D, 2hdd_A, 1e3o_C, 2xsd_C, 7xrc_C, 1le8_B, 4qtr_D, 1du0_A, 4xrm_B |
| Binding Motifs: | MA0209.1 yTAATKA ap TAATnn |
| Binding Sites: | MA0209.1.16 MA0209.1.12 MA0209.1.17 MA0209.1.7 MA0209.1.1 MA0209.1.10 MA0209.1.11 MA0209.1.13 MA0209.1.14 MA0209.1.15 MA0209.1.18 MA0209.1.19 MA0209.1.2 MA0209.1.20 MA0209.1.3 MA0209.1.4 MA0209.1.5 MA0209.1.6 MA0209.1.8 MA0209.1.9 |
| Publications: | Yan Shian-Jang, Gu Yi, Li Willis X., Fleming Robert J. Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development.. Development 131:285-298 (2004). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.